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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MQSIRSSTRL LQRHRFSISN TLRFTSSSSS SGSWSENESR MVGFDSFPCT RAATYLISSL

70 80 90 100 110 120
KNVGFSSSAI PKQDFKYSLR CFSTTGDSVQ STPQGSPESD CVVPQRIKFK RLDKTAKHIM

130 140 150 160 170 180
QIVDKEAVEE VRNLREIPEI KPGYIVQLKV EVPENKRRVS IVKGVVIARR NAGLNSTFRI

190 200 210 220
RRLVAGVGVE SMFPLYSPNL REIKVVDKKK VRRAKLYYLR DKVNALKKH


References and documentation are available.

Number of amino acids: 229 Molecular weight: 26030.10 Theoretical pI: 10.40
Amino acid composition: 
Ala (A) 10 4.4% Arg (R) 23 10.0% Asn (N) 9 3.9% Asp (D) 8 3.5% Cys (C) 3 1.3% Gln (Q) 8 3.5% Glu (E) 12 5.2% Gly (G) 10 4.4% His (H) 3 1.3% Ile (I) 14 6.1% Leu (L) 16 7.0% Lys (K) 20 8.7% Met (M) 4 1.7% Phe (F) 10 4.4% Pro (P) 10 4.4% Ser (S) 30 13.1% Thr (T) 10 4.4% Trp (W) 1 0.4% Tyr (Y) 6 2.6% Val (V) 22 9.6% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 20 Total number of positively charged residues (Arg + Lys): 43 Atomic composition: Carbon C 1148 Hydrogen H 1884 Nitrogen N 342 Oxygen O 333 Sulfur S 7 Formula: C1148H1884N342O333S7 Total number of atoms: 3714 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 14565 Abs 0.1% (=1 g/l) 0.560, assuming all pairs of Cys residues form cystines Ext. coefficient 14440 Abs 0.1% (=1 g/l) 0.555, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 58.30 This classifies the protein as unstable. Aliphatic index: 83.32 Grand average of hydropathicity (GRAVY): -0.450