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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MQSVNNATSS TPIFGVSQPI STAFPKANDV ALTSSLQSSL EEFKSFESKQ ETLLRIKVLK

70 80 90 100 110 120
NLDGLVKDWV QKTTISRIPK DQMFNAGGKL IPFGSYRLGV HSSGADIDSI VVAPRHITRS

130 140 150 160 170 180
DFFNSFKDIL AKNPEVTELC AVEKAFVPIM TLKYSGVDID ILFARLALKS VPEDLNILDD

190 200 210 220 230 240
SLLKNLDEES VRSLNGCRVA EQLLKLVPHQ KNFCITLRAI KLWAKNHGIY SNSMGFFGGI

250 260 270 280 290 300
TWAILVARIC QLYPNAAPSR LIQKVFFIFS TWNWPAPVLL DYINCDRTDL AQLNQLVWDP

310 320 330 340 350 360
RRNHADRYHL MPIITPAFPQ QNSTHNVSRS SMKVIQDEMK KALIICDKIH EGTLEWRDLL

370 380 390 400 410 420
EEINFFSKYH HFIALKLKAE SVKEELAFGG FFESRIRQLV QILEKNQVIQ VAQINPRKFK

430 440 450 460 470 480
DVKDPKKSIW FIGLEFVANV KNVDLTSDIQ QFKMNIDRQS MSVKEIAAGC QVETDFTYEK

490 500 510 520 530 540
RSNLINIISK KDLSCQRIMK KTEVSVPVTK DSRNLKRHIL DEAPTVQKKH KLDVLEKSTV

550
DSLLSTLKKN TSHA


References and documentation are available.

Number of amino acids: 554 Molecular weight: 63007.96 Theoretical pI: 9.21
Amino acid composition: 
Ala (A) 33 6.0% Arg (R) 25 4.5% Asn (N) 30 5.4% Asp (D) 33 6.0% Cys (C) 8 1.4% Gln (Q) 26 4.7% Glu (E) 28 5.1% Gly (G) 18 3.2% His (H) 13 2.3% Ile (I) 45 8.1% Leu (L) 56 10.1% Lys (K) 50 9.0% Met (M) 10 1.8% Phe (F) 29 5.2% Pro (P) 22 4.0% Ser (S) 47 8.5% Thr (T) 26 4.7% Trp (W) 8 1.4% Tyr (Y) 8 1.4% Val (V) 39 7.0% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 61 Total number of positively charged residues (Arg + Lys): 75 Atomic composition: Carbon C 2836 Hydrogen H 4537 Nitrogen N 769 Oxygen O 814 Sulfur S 18 Formula: C2836H4537N769O814S18 Total number of atoms: 8974 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 56420 Abs 0.1% (=1 g/l) 0.895, assuming all pairs of Cys residues form cystines Ext. coefficient 55920 Abs 0.1% (=1 g/l) 0.888, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 39.90 This classifies the protein as stable. Aliphatic index: 97.47 Grand average of hydropathicity (GRAVY): -0.209