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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MQTISGVLPT VLSPSELRSD DERTFQFDEE AEITTHLTES EDLRRLINET AQLGVRVDHI

70 80 90 100 110 120
HDKTDQEIAR LEKVIKEVTE SDTFFRSCSG WFKTNKNFSD SESSSNTQLK SLSQLHGRYD

130 140 150 160 170 180
RDWRQRLNKW FRKNKSKLAL PSDNNLEEVN DDKVYGYGED LMERGKTPYF SDIDDFMNGL

190 200 210 220 230 240
NIISPLTPDD FENDDTLVKI DETCQIHSAS EPEKTSISPT FGKNIKKELV TDDTESIISG

250 260 270 280 290 300
PPLQENKKTL LKYRYVRTSL DMLGSEKSSS KNNSGGMFRI FHKSANFGDK NQENVPRVWD

310 320 330 340 350 360
TLRNNLGREI YLLQGRFKKW TTKHQNLKKG QPCKDEDAVT VPLPSSDPGK ETQLETKLCF

370
VPEPGDQPLV QA


References and documentation are available.

Number of amino acids: 372 Molecular weight: 42594.46 Theoretical pI: 5.32
Amino acid composition: 
Ala (A) 8 2.2% Arg (R) 20 5.4% Asn (N) 22 5.9% Asp (D) 32 8.6% Cys (C) 4 1.1% Gln (Q) 16 4.3% Glu (E) 31 8.3% Gly (G) 19 5.1% His (H) 7 1.9% Ile (I) 17 4.6% Leu (L) 34 9.1% Lys (K) 32 8.6% Met (M) 5 1.3% Phe (F) 16 4.3% Pro (P) 18 4.8% Ser (S) 34 9.1% Thr (T) 28 7.5% Trp (W) 5 1.3% Tyr (Y) 7 1.9% Val (V) 17 4.6% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 63 Total number of positively charged residues (Arg + Lys): 52 Atomic composition: Carbon C 1861 Hydrogen H 2937 Nitrogen N 521 Oxygen O 606 Sulfur S 9 Formula: C1861H2937N521O606S9 Total number of atoms: 5934 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 38180 Abs 0.1% (=1 g/l) 0.896, assuming all pairs of Cys residues form cystines Ext. coefficient 37930 Abs 0.1% (=1 g/l) 0.890, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 42.29 This classifies the protein as unstable. Aliphatic index: 68.87 Grand average of hydropathicity (GRAVY): -0.892