ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MQVTTRFISA IVSFCLFASF TLAENSARAT PGSDLLVLTE KKFKSFIESH PLVLVEFFAP 

        70         80         90        100        110        120 
WCLHSQILRP HLEEAASILK EHNVPVVQID CEANSMVCLQ QTINTYPTLK IFKNGRIFDG 

       130        140        150        160        170        180 
QVYRGVKITD EITQYMIQLY EASVIYLNSE DEIQPYLENA TLPVVINRGL TGLNETYQEV 

       190        200        210        220        230        240 
ALDLAEDYVF LSLLDSEDKS LSIHLPNTTE PILFDGNVDS LVGNSVALTQ WLKVVILPYF 

       250        260        270        280        290        300 
TDIEPDLFPK YISSNLPLAY FFYTSEEELE DYTDLFTQLG KENRGQINFI ALNSTMFPHH 

       310        320        330        340        350        360 
VRFLNMREQF PLFAIHNMIN NLKYGLPQLP EEEYAKLEKP QPLDRDMIVQ LVKDYREGTA 

       370        380        390        400        410        420 
KPIVKSEEIP KEQKSNVYKI VGKTHDDIVH DDDKDVLVKY YATWCIHSKR FAPIYEEIAN 

       430        440        450        460        470        480 
VLASDESVRD KILIAEVDSG ANDILSFPVT GYPTIALYPA GNNSKPIIFN KIRNLEDVFE 

       490        500        510 
FIKESGTHHI DGQAIYDKLH QAKDSEVSTE DTVHDEL 

References and documentation are available.

Number of amino acids: 517

Molecular weight: 58982.08

Theoretical pI: 4.79

Amino acid composition: 
Ala (A)  29	  5.6%
Arg (R)  14	  2.7%
Asn (N)  27	  5.2%
Asp (D)  34	  6.6%
Cys (C)   5	  1.0%
Gln (Q)  20	  3.9%
Glu (E)  43	  8.3%
Gly (G)  18	  3.5%
His (H)  15	  2.9%
Ile (I)  42	  8.1%
Leu (L)  54	 10.4%
Lys (K)  30	  5.8%
Met (M)   7	  1.4%
Phe (F)  27	  5.2%
Pro (P)  27	  5.2%
Ser (S)  33	  6.4%
Thr (T)  29	  5.6%
Trp (W)   3	  0.6%
Tyr (Y)  23	  4.4%
Val (V)  37	  7.2%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 77
Total number of positively charged residues (Arg + Lys): 44

Atomic composition:

Carbon      C	      2680
Hydrogen    H	      4141
Nitrogen    N	       669
Oxygen      O	       804
Sulfur      S	        12

Formula: C2680H4141N669O804S12
Total number of atoms: 8306

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    51020
Abs 0.1% (=1 g/l)   0.865, assuming all pairs of Cys residues form cystines


Ext. coefficient    50770
Abs 0.1% (=1 g/l)   0.861, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 36.08
This classifies the protein as stable.



Aliphatic index: 98.78

Grand average of hydropathicity (GRAVY): -0.171