ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MQYKNRLTLA AVLAASVSAA NSTQSVPSSC SIKSDATASS QADLDSYSGC STIVGDLVLT 

        70         80         90        100        110        120 
GDLASAALAG VEEIDGSLTI KNATQMTSFS ADSLKKISET LTLNQLTVLD TASFGSLEEV 

       130        140        150        160        170        180 
DTISFVTLPA VSNIITKLTS AKQITIADTA LESIAGFEDL DEIEVFNVNN NKGLASIDSK 

       190        200        210        220        230        240 
LKHVKTALEI TFNGQSAEIS FDELEWANNI TLRDVSSASF AKLSNVNASL GFINNSLPSI 

       250        260        270        280        290        300 
DLSTLEKIGG SLSIVSNEEL TELDFSNLTS VGGGFVIANN SKLATIDTFS ELSTIGGALV 

       310        320        330        340        350        360 
VTGKFGDLEF PSLKSVKGGA DIESTASNFS CDALNKLQQK GGIQGDSFVC KDGQTSTSVK 

       370        380        390        400        410 
LTATGTSDDD DSTATSDSGS AGSSTTSSSK SSGAAAHFNA PGSSVMGAVA AIAYALL 

References and documentation are available.

Number of amino acids: 417

Molecular weight: 42733.36

Theoretical pI: 4.30

Amino acid composition: 
Ala (A)  46	 11.0%
Arg (R)   2	  0.5%
Asn (N)  23	  5.5%
Asp (D)  28	  6.7%
Cys (C)   4	  1.0%
Gln (Q)  11	  2.6%
Glu (E)  20	  4.8%
Gly (G)  31	  7.4%
His (H)   2	  0.5%
Ile (I)  26	  6.2%
Leu (L)  43	 10.3%
Lys (K)  22	  5.3%
Met (M)   3	  0.7%
Phe (F)  17	  4.1%
Pro (P)   5	  1.2%
Ser (S)  67	 16.1%
Thr (T)  38	  9.1%
Trp (W)   1	  0.2%
Tyr (Y)   3	  0.7%
Val (V)  25	  6.0%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 48
Total number of positively charged residues (Arg + Lys): 24

Atomic composition:

Carbon      C	      1850
Hydrogen    H	      2990
Nitrogen    N	       484
Oxygen      O	       656
Sulfur      S	         7

Formula: C1850H2990N484O656S7
Total number of atoms: 5987

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    10220
Abs 0.1% (=1 g/l)   0.239, assuming all pairs of Cys residues form cystines


Ext. coefficient     9970
Abs 0.1% (=1 g/l)   0.233, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 30.63
This classifies the protein as stable.



Aliphatic index: 92.95

Grand average of hydropathicity (GRAVY): 0.091