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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MRAFPRVLPF RHQRSYNNIL LRTVRLFGSS LSSFDFSRQM PKVDPDNTAA MLLQKNLIQR

70 80 90 100 110 120
NNMLYGYGSG TIRCTLLDST GRAKSPLVEI KREDLVSKHG LLPRDLRKIE KSRKNDLVPS

130 140 150 160 170 180
LLVRENSILI SLLTVKALIK PDMVIIFDSA GSGITLNSEA HKDFINDMKL RLKNQETSEL

190 200 210 220 230 240
NSDPLPYEFR ALETIFISAL SNLTSEMKVL LTICKGVLQD LEFSITRDKL RFLLGQNKKL

250 260 270 280 290 300
SSFNKKAVLV KDMLDDLLEQ DDMLCDMYLT DKKAGKIRVQ DDHTEIEMLL ETYHNYVDEI

310 320 330 340 350 360
VQKSESAISD VKTTEEIINI ILDSNRNELM LLGIRYAIGM LSLGGALFLG SIYGMNLESF

370 380 390 400 410
IEESNYAYLT VTILGLISTV WLYAKGIRHL HKLQRMTLLS KIKTDSVHEL LKK


References and documentation are available.

Number of amino acids: 413 Molecular weight: 47082.91 Theoretical pI: 8.83
Amino acid composition: 
Ala (A) 16 3.9% Arg (R) 24 5.8% Asn (N) 21 5.1% Asp (D) 27 6.5% Cys (C) 3 0.7% Gln (Q) 11 2.7% Glu (E) 24 5.8% Gly (G) 19 4.6% His (H) 8 1.9% Ile (I) 32 7.7% Leu (L) 66 16.0% Lys (K) 32 7.7% Met (M) 15 3.6% Phe (F) 14 3.4% Pro (P) 10 2.4% Ser (S) 36 8.7% Thr (T) 22 5.3% Trp (W) 1 0.2% Tyr (Y) 12 2.9% Val (V) 20 4.8% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 51 Total number of positively charged residues (Arg + Lys): 56 Atomic composition: Carbon C 2100 Hydrogen H 3440 Nitrogen N 566 Oxygen O 618 Sulfur S 18 Formula: C2100H3440N566O618S18 Total number of atoms: 6742 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 23505 Abs 0.1% (=1 g/l) 0.499, assuming all pairs of Cys residues form cystines Ext. coefficient 23380 Abs 0.1% (=1 g/l) 0.497, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 42.95 This classifies the protein as unstable. Aliphatic index: 110.46 Grand average of hydropathicity (GRAVY): -0.122