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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MREESRSRKR KHIPVDIEEV EVRSKYFKKN ERTVELVKEN KINKDLQNYG GVNIDWIKAL

70 80 90 100 110 120
KPIEYFEWIE SRTCDDPRTW GRPITKEEMI NDSGAKVPES FLPIYNRVRL MRSKVKTPVD

130 140 150 160 170 180
AMGCSMIPVL VSNKCGIPSE KVDPKNFRLQ FLIGTMLSAQ TRDERMAQAA LNITEYCLNT

190 200 210 220 230 240
LKIAEGITLD GLLKIDEPVL ANLIRCVSFY TRKANFIKRT AQLLVDNFDS DIPYDIEGIL

250 260 270 280 290 300
SLPGVGPKMG YLTLQKGWGL IAGICVDVHV HRLCKMWNWV DPIKCKTAEH TRKELQVWLP

310 320 330 340 350 360
HSLWYEINTV LVGFGQLICM ARGKRCDLCL ANDVCNARNE KLIESSKFHQ LEDKEDIEKV

370 380
YSHWLDTVTN GITTERHKKK


References and documentation are available.

Number of amino acids: 380 Molecular weight: 43843.94 Theoretical pI: 8.78
Amino acid composition: 
Ala (A) 16 4.2% Arg (R) 24 6.3% Asn (N) 20 5.3% Asp (D) 22 5.8% Cys (C) 12 3.2% Gln (Q) 9 2.4% Glu (E) 29 7.6% Gly (G) 20 5.3% His (H) 8 2.1% Ile (I) 30 7.9% Leu (L) 35 9.2% Lys (K) 35 9.2% Met (M) 10 2.6% Phe (F) 10 2.6% Pro (P) 16 4.2% Ser (S) 18 4.7% Thr (T) 20 5.3% Trp (W) 9 2.4% Tyr (Y) 10 2.6% Val (V) 27 7.1% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 51 Total number of positively charged residues (Arg + Lys): 59 Atomic composition: Carbon C 1952 Hydrogen H 3131 Nitrogen N 541 Oxygen O 560 Sulfur S 22 Formula: C1952H3131N541O560S22 Total number of atoms: 6206 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 65150 Abs 0.1% (=1 g/l) 1.486, assuming all pairs of Cys residues form cystines Ext. coefficient 64400 Abs 0.1% (=1 g/l) 1.469, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 42.45 This classifies the protein as unstable. Aliphatic index: 91.53 Grand average of hydropathicity (GRAVY): -0.384