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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MRFLSKRILK PVLSVIILIS IAVTVVLYFL TANENYLQAV KDSAKSQYAS LRESYKSITG

70 80 90 100 110 120
KTESADELPD HDAEVLDSIM DRLHEPLYEK DTFDPNEVLA ENKQLYEEFL LQEISEPKVD

130 140 150 160 170 180
NLVRSGDPLA GKAKGTILSL VRNSDLEDII SSIQQLEEEY NKNFGYPYTF LNDEEFTDEF

190 200 210 220 230 240
KDGIKSILPK DRVVEFGTIG PDNWNMPDSI DRERYDQEMD KMSKENIQYA EVESYHNMCR

250 260 270 280 290 300
FYSKEFYHHP LLSKYKYVWR LEPNVNFYCK INYDVFQFMN KNDKIYGFVL NLYDSPQTIE

310 320 330 340 350 360
TLWTSTMDFV EEHPNYLNVN GAFAWLKDNS QNPKNYDYTQ GYSTCHFWTN FEIVDLDFLR

370 380 390 400 410 420
SEPYEKYMQY LEEKGGFYYE RWGDAPVRSL ALALFADKSS IHWFRDIGYH HTPYTNCPTC

430 440 450 460
PADSDRCNGN CVPGKFTPWS DLDNQNCQAT WIRHSMSEEE LEMY


References and documentation are available.

Number of amino acids: 464 Molecular weight: 54555.99 Theoretical pI: 4.72
Amino acid composition: 
Ala (A) 19 4.1% Arg (R) 17 3.7% Asn (N) 31 6.7% Asp (D) 36 7.8% Cys (C) 8 1.7% Gln (Q) 15 3.2% Glu (E) 41 8.8% Gly (G) 17 3.7% His (H) 11 2.4% Ile (I) 24 5.2% Leu (L) 40 8.6% Lys (K) 29 6.2% Met (M) 11 2.4% Phe (F) 24 5.2% Pro (P) 22 4.7% Ser (S) 34 7.3% Thr (T) 21 4.5% Trp (W) 9 1.9% Tyr (Y) 32 6.9% Val (V) 23 5.0% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 77 Total number of positively charged residues (Arg + Lys): 46 Atomic composition: Carbon C 2458 Hydrogen H 3665 Nitrogen N 621 Oxygen O 752 Sulfur S 19 Formula: C2458H3665N621O752S19 Total number of atoms: 7515 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 97680 Abs 0.1% (=1 g/l) 1.790, assuming all pairs of Cys residues form cystines Ext. coefficient 97180 Abs 0.1% (=1 g/l) 1.781, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 44.56 This classifies the protein as unstable. Aliphatic index: 72.26 Grand average of hydropathicity (GRAVY): -0.625