ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MRGDGIRARK ALGQNFLTDR SVLSRIAALV SAGAGERILE IGPGKGALTS YLAEQAGQLV 

        70         80         90        100        110        120 
AVELDDRLVP LLRGSFAGNP SVTIIEGDIL DLDLRETLGR YGTPPWKVAA NLPYNISTPV 

       130        140        150        160        170        180 
LFRLLDARDL FSRLVLMLQK EVGNRLAAGP GSKEYGVLSV LFQLHFDVTR EILVRPGSFH 

       190        200        210        220        230        240 
PVPKVDSVVL LFVPLAQPRV DVGDEDYFRR VVKASFAMRR KTLWNCLKGG ALGVPTDGIR 

       250        260        270 
DVLARCGIDE GRRGETLSLQ EFASLTKGLL AAGGSL 

References and documentation are available.

Number of amino acids: 276

Molecular weight: 29860.63

Theoretical pI: 9.32

Amino acid composition: 
Ala (A)  24	  8.7%
Arg (R)  25	  9.1%
Asn (N)   6	  2.2%
Asp (D)  17	  6.2%
Cys (C)   2	  0.7%
Gln (Q)   7	  2.5%
Glu (E)  13	  4.7%
Gly (G)  30	 10.9%
His (H)   2	  0.7%
Ile (I)  11	  4.0%
Leu (L)  42	 15.2%
Lys (K)  10	  3.6%
Met (M)   3	  1.1%
Phe (F)  11	  4.0%
Pro (P)  14	  5.1%
Ser (S)  16	  5.8%
Thr (T)  11	  4.0%
Trp (W)   2	  0.7%
Tyr (Y)   5	  1.8%
Val (V)  25	  9.1%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 30
Total number of positively charged residues (Arg + Lys): 35

Atomic composition:

Carbon      C	      1338
Hydrogen    H	      2178
Nitrogen    N	       380
Oxygen      O	       382
Sulfur      S	         5

Formula: C1338H2178N380O382S5
Total number of atoms: 4283

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    18575
Abs 0.1% (=1 g/l)   0.622, assuming all pairs of Cys residues form cystines


Ext. coefficient    18450
Abs 0.1% (=1 g/l)   0.618, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 31.01
This classifies the protein as stable.



Aliphatic index: 109.86

Grand average of hydropathicity (GRAVY): 0.099