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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MRGEIDEANL APETSLINKE NQDSSATITT TLLLTTFVAV SGSFVFGSAI GYSSPVQSDL

70 80 90 100 110 120
TKELNLSVAE YSLFGSILTI GAMIGAAMSG RIADMIGRRA TMGFSEMFCI LGWLAIYLSK

130 140 150 160 170 180
VAIWLDVGRF LVGYGMGVFS FVVPVYIAEI TPKGLRGGFT TVHQLLICLG VSVTYLLGSF

190 200 210 220 230 240
IGWRILALIG MIPCVVQMMG LFVIPESPRW LAKVGKWEEF EIALQRLRGE SADISYESNE

250 260 270 280 290 300
IKDYTRRLTD LSEGSIVDLF QPQYAKSLVV GVGLMVLQQF GGVNGIAFYA SSIFESAGVS

310 320 330 340 350 360
SKIGMIAMVV VQIPMTTLGV LLMDKSGRRP LLLISATGTC IGCFLVGLSF SLQFVKQLSG

370 380 390 400 410 420
DASYLALTGV LVYTGSFSLG MGGIPWVIMS EIFPIDIKGS AGSLVTVVSW VGSWIISFTF

430 440 450 460 470
NFLMNWNPAG TFYVFATVCG ATVIFVAKLV PETKGRTLEE IQYSIGYVEL


References and documentation are available.

Number of amino acids: 470 Molecular weight: 50739.53 Theoretical pI: 5.20
Amino acid composition: 
Ala (A) 31 6.6% Arg (R) 15 3.2% Asn (N) 9 1.9% Asp (D) 12 2.6% Cys (C) 6 1.3% Gln (Q) 13 2.8% Glu (E) 22 4.7% Gly (G) 51 10.9% His (H) 1 0.2% Ile (I) 41 8.7% Leu (L) 52 11.1% Lys (K) 14 3.0% Met (M) 18 3.8% Phe (F) 28 6.0% Pro (P) 14 3.0% Ser (S) 45 9.6% Thr (T) 29 6.2% Trp (W) 9 1.9% Tyr (Y) 15 3.2% Val (V) 45 9.6% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 34 Total number of positively charged residues (Arg + Lys): 29 Atomic composition: Carbon C 2332 Hydrogen H 3660 Nitrogen N 562 Oxygen O 650 Sulfur S 24 Formula: C2332H3660N562O650S24 Total number of atoms: 7228 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 72225 Abs 0.1% (=1 g/l) 1.423, assuming all pairs of Cys residues form cystines Ext. coefficient 71850 Abs 0.1% (=1 g/l) 1.416, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 33.33 This classifies the protein as stable. Aliphatic index: 111.53 Grand average of hydropathicity (GRAVY): 0.652