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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MRIQSLFVLF NVAIIAWSYP YEPLRVLQVG ENEVMEVPES EKLNLRRRGV KFFDVTKHTS

70 80 90 100 110 120
FLPFFNKEEE PTVPTYNYPP EISNKEVVDD SIKNIDKGSM HKNLAKFTSF YTRYYKSDHG

130 140 150 160 170 180
FESAEWLAAT IANITKDIPQ DTLTIEHFDH KEWKQYSIIV RVTGSTTPED IIIIGSHQDS

190 200 210 220 230 240
INLLLPSIMA APGADDNGSG TVTNMEALRL YTENFLKRGF RPNNTVEFHF YSAEEGGLLG

250 260 270 280 290 300
SLDVFTAYAK QKKHVRAMLQ QDMTGYVSDP EDEHVGIVTD YTTPALTDFI KLIINSYLSI

310 320 330 340 350 360
PYRDTQCGYA CSDHGSATRN GFPGSFVIES EFKKTNKYIH STMDTLDRLS LAHMAEHTKI

370
VLGVIIELGS WSAW


References and documentation are available.

Number of amino acids: 374 Molecular weight: 42484.04 Theoretical pI: 5.48
Amino acid composition: 
Ala (A) 21 5.6% Arg (R) 14 3.7% Asn (N) 18 4.8% Asp (D) 22 5.9% Cys (C) 2 0.5% Gln (Q) 9 2.4% Glu (E) 27 7.2% Gly (G) 21 5.6% His (H) 13 3.5% Ile (I) 28 7.5% Leu (L) 28 7.5% Lys (K) 22 5.9% Met (M) 9 2.4% Phe (F) 20 5.3% Pro (P) 17 4.5% Ser (S) 29 7.8% Thr (T) 29 7.8% Trp (W) 5 1.3% Tyr (Y) 17 4.5% Val (V) 23 6.1% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 49 Total number of positively charged residues (Arg + Lys): 36 Atomic composition: Carbon C 1917 Hydrogen H 2936 Nitrogen N 496 Oxygen O 575 Sulfur S 11 Formula: C1917H2936N496O575S11 Total number of atoms: 5935 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 52955 Abs 0.1% (=1 g/l) 1.246, assuming all pairs of Cys residues form cystines Ext. coefficient 52830 Abs 0.1% (=1 g/l) 1.244, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 40.45 This classifies the protein as unstable. Aliphatic index: 81.84 Grand average of hydropathicity (GRAVY): -0.313