ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MRLHYLLRLL SFAFLWFILR SFLVKYLNFF TLGFFFCFSS TPRNFAYLVA LFMLCLSTFS 

        70         80         90        100        110        120 
AFSNLTLFSW AKYSKLSLGS NVSNSTVVES SYISVIAPFF KIGFTLLSLL SLSPSSLSES 

       130        140        150        160        170        180 
NPCQDSSDST CKSSVLSFFA SSISASKFKL SLNVFNCSSI TSLRSCRIFC LSSIFLSLSC 

       190 
SLINSCAFFC L 

References and documentation are available.

Number of amino acids: 191

Molecular weight: 21327.01

Theoretical pI: 9.23

Amino acid composition: 
Ala (A)   9	  4.7%
Arg (R)   6	  3.1%
Asn (N)   9	  4.7%
Asp (D)   2	  1.0%
Cys (C)  10	  5.2%
Gln (Q)   1	  0.5%
Glu (E)   2	  1.0%
Gly (G)   3	  1.6%
His (H)   1	  0.5%
Ile (I)   9	  4.7%
Leu (L)  33	 17.3%
Lys (K)   7	  3.7%
Met (M)   2	  1.0%
Phe (F)  26	 13.6%
Pro (P)   4	  2.1%
Ser (S)  44	 23.0%
Thr (T)   8	  4.2%
Trp (W)   2	  1.0%
Tyr (Y)   5	  2.6%
Val (V)   8	  4.2%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 4
Total number of positively charged residues (Arg + Lys): 13

Atomic composition:

Carbon      C	       993
Hydrogen    H	      1510
Nitrogen    N	       230
Oxygen      O	       267
Sulfur      S	        12

Formula: C993H1510N230O267S12
Total number of atoms: 3012

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    19075
Abs 0.1% (=1 g/l)   0.894, assuming all pairs of Cys residues form cystines


Ext. coefficient    18450
Abs 0.1% (=1 g/l)   0.865, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 43.70
This classifies the protein as unstable.



Aliphatic index: 102.62

Grand average of hydropathicity (GRAVY): 0.807