ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MRLKREALQS SIAGTKDIGR KEVLHVNLTN ESVLSAYKHM LFMRRLEEKV GQLYGMGLIR 

        70         80         90        100        110        120 
GFCHLYIGQE AVAAGMYSVL QPSDSVITSY REHGFALSSG ESPGKIIAEL LGRSAGSSKG 

       130        140        150        160        170        180 
KGGSMHIFNV QKNFYGGHGI VGAQVPIGTG IAFANKYKAN GGVVFTCLGD GAINQGQVYE 

       190        200        210        220        230        240 
AFNMAALWKL PVVYVVENNE YAMGTSVARS SYVSDLYKRG ESCGVPGRRV DGMDLFEVIR 

       250        260        270        280        290        300 
EVSQAAAHCR EGNGPILLEM KTYRYRGHSM SDPAKYRTRE EVEEIRNNRD PLCIVKSHIL 

       310        320        330        340 
EHNMASEEVL TTWEKEIRDE IKKAVEFAEG CPEPSVEELY TDVYK 

References and documentation are available.

Number of amino acids: 345

Molecular weight: 38180.52

Theoretical pI: 6.81

Amino acid composition: 
Ala (A)  26	  7.5%
Arg (R)  21	  6.1%
Asn (N)  14	  4.1%
Asp (D)  10	  2.9%
Cys (C)   6	  1.7%
Gln (Q)   9	  2.6%
Glu (E)  32	  9.3%
Gly (G)  36	 10.4%
His (H)  10	  2.9%
Ile (I)  19	  5.5%
Leu (L)  25	  7.2%
Lys (K)  20	  5.8%
Met (M)  12	  3.5%
Phe (F)  10	  2.9%
Pro (P)  10	  2.9%
Ser (S)  26	  7.5%
Thr (T)  11	  3.2%
Trp (W)   2	  0.6%
Tyr (Y)  17	  4.9%
Val (V)  29	  8.4%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 42
Total number of positively charged residues (Arg + Lys): 41

Atomic composition:

Carbon      C	      1681
Hydrogen    H	      2655
Nitrogen    N	       473
Oxygen      O	       507
Sulfur      S	        18

Formula: C1681H2655N473O507S18
Total number of atoms: 5334

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    36705
Abs 0.1% (=1 g/l)   0.961, assuming all pairs of Cys residues form cystines


Ext. coefficient    36330
Abs 0.1% (=1 g/l)   0.952, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 40.91
This classifies the protein as unstable.



Aliphatic index: 81.65

Grand average of hydropathicity (GRAVY): -0.290