ProtParam
User-provided sequence:
10 20 30 40 50 60
MRLLIALLSL ATYADSLYFH IAETEKKCFI EEIPDETMVT GNYKVQLYDP NTKGYGDYPN
70 80 90 100 110 120
IGMHVEVKDP EDKVILSKLY TAEGRFTFTS NTPGEHVICI YSNSTAWFNG AQLRVHLDIQ
130 140 150 160 170 180
AGDHAQDYAQ IAQKDKLNEL QLRIRQLLDQ VDQITKEQNY QRYREERFRQ TSESTNSRVF
190 200 210
YWSIAQVVVL AITGAWQMRH LRGFFEAKKL V
References and
documentation are available.
Number of amino acids: 211
Molecular weight: 24523.80
Theoretical pI: 6.08
Total number of negatively charged residues (Asp + Glu): 27
Total number of positively charged residues (Arg + Lys): 24
Atomic composition:
Carbon C 1101
Hydrogen H 1704
Nitrogen N 298
Oxygen O 326
Sulfur S 6
Formula: C
1101H
1704N
298O
326S
6
Total number of atoms: 3435
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 34505
Abs 0.1% (=1 g/l) 1.407, assuming all pairs of Cys residues form cystines
Ext. coefficient 34380
Abs 0.1% (=1 g/l) 1.402, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 30.05
This classifies the protein as stable.
Aliphatic index: 85.97
Grand average of hydropathicity (GRAVY): -0.436