ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MRLSNLIASA SLLSAATLAA PANHEHKDKR AVVTTTVQKQ TTIIVNGAAS TPVAALEENA 

        70         80         90        100        110        120 
VVNSAPAAAT STTSSAASVA TAAASSSENN SQVSAAASPA SSSAATSTQS SSSSQASSSS 

       130        140        150        160        170        180 
SSGEDVSSFA SGVRGITYTP YESSGACKSA SEVASDLAQL TDFPVIRLYG TDCNQVENVF 

       190        200        210        220        230        240 
KAKASNQKVF LGIYYVDQIQ DGVNTIKSAV ESYGSWDDVT TVSIGNELVN GNQATPSQVG 

       250        260        270        280        290        300 
QYIDSGRSAL KAAGYTGPVV SVDTFIAVIN NPELCDYSDY MAVNAHAYFD KNTVAQDSGK 

       310        320        330        340        350        360 
WLLEQIQRVW TACDGKKNVV ITESGWPSKG ETYGVAVPSK ENQKDAVSAI TSSCGADTFL 

       370        380 
FTAFNDYWKA DGAYGVEKYW GILSNE 

References and documentation are available.

Number of amino acids: 386

Molecular weight: 40173.03

Theoretical pI: 4.68

Amino acid composition: 
Ala (A)  55	 14.2%
Arg (R)   6	  1.6%
Asn (N)  22	  5.7%
Asp (D)  20	  5.2%
Cys (C)   5	  1.3%
Gln (Q)  17	  4.4%
Glu (E)  17	  4.4%
Gly (G)  24	  6.2%
His (H)   3	  0.8%
Ile (I)  16	  4.1%
Leu (L)  17	  4.4%
Lys (K)  18	  4.7%
Met (M)   2	  0.5%
Phe (F)   9	  2.3%
Pro (P)  11	  2.8%
Ser (S)  57	 14.8%
Thr (T)  30	  7.8%
Trp (W)   6	  1.6%
Tyr (Y)  15	  3.9%
Val (V)  36	  9.3%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 37
Total number of positively charged residues (Arg + Lys): 24

Atomic composition:

Carbon      C	      1744
Hydrogen    H	      2723
Nitrogen    N	       473
Oxygen      O	       602
Sulfur      S	         7

Formula: C1744H2723N473O602S7
Total number of atoms: 5549

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    55600
Abs 0.1% (=1 g/l)   1.384, assuming all pairs of Cys residues form cystines


Ext. coefficient    55350
Abs 0.1% (=1 g/l)   1.378, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 32.36
This classifies the protein as stable.



Aliphatic index: 74.64

Grand average of hydropathicity (GRAVY): -0.164