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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MRNAGVQVDT NMQKISLQDT VLVNEMKGRV KFIGETQFAK GIWYGIELDK PLGKNDGSAN

70 80 90 100 110 120
GIRYFDIDLK KANSNGGYYG LFCKKDTLQF YKPDDDEHSL LNGNAAQETI KNLQVKCESL

130 140 150 160 170 180
ASKLNKIKIE NHELKTSVEK LSTNETVLLS KISRLDKLVK ELKVENGNMK THLDNFNHLL

190 200 210 220 230 240
DASDSVMAPD LDKGTLLERS HLLQGLLDQT KLSYDKAMKV QEDLLEENTQ LLEENAVLSK

250 260 270 280 290 300
KISDLGLQLQ QTNNTIGDLA LQIEAQSKSS NIVDKLTNDN ILLTSNIKAL NNELEELQAK

310 320 330 340 350 360
EKLDENLRIT YEQLEQELRL QLSNLQSALE NEKEIAGTYI EENSRLKATL ESIEAKTSHK

370 380 390 400 410 420
FQSLELKVNT LQEELYQNKL LKKFYQIYEP FAQPHLAALS SQLQYLAEVI ESENFGKLEN

430 440 450 460 470 480
IEIHIILKVL SSISYALHIY TIKNTPDHLE TTLQCFKVNI APISMWLSEF LQRKFSSKQE

490 500 510 520 530 540
TAFSICQFLE DNKFLDKDVT LILKILHPIL ETTVPKLLAF LRTNSNFNDN DTLCLIGSLY

550 560 570 580 590 600
ERSLSLIARI DKLIGKEEIS KQDNRLFLYP SCDITLSSIL TILFSDALFL RQDYKRISSL

610 620 630 640 650 660
KKLEVFFQGI ESLLENITIF PEQPSQQTSD SESQCNIKEG NFSNSLLSDR LNEENIRLKE

670 680 690 700 710 720
VLVQKENMLT ELETKIKIII GRDLERKTLE ENIKTLKVEL NNKNEENCGK TEILNKLKEE

730 740 750 760 770 780
NFNLVNRLKN MELKLYQIKD NNTLNKIYLD REKVDRVNLV SEIMELRETI RRQIKEQKRV

790 800 810 820 830 840
SIDFSWLDEL PAVENKQPFK EHINHSLDTL GIEMFNFVST SRILDLKLDQ PLAEDELWHE

850 860
RDHSYISYLK RKRKNIRLKS QNVVTYYK


References and documentation are available.

Number of amino acids: 868 Molecular weight: 100289.71 Theoretical pI: 5.62
Amino acid composition: 
Ala (A) 31 3.6% Arg (R) 31 3.6% Asn (N) 69 7.9% Asp (D) 48 5.5% Cys (C) 8 0.9% Gln (Q) 46 5.3% Glu (E) 85 9.8% Gly (G) 26 3.0% His (H) 15 1.7% Ile (I) 66 7.6% Leu (L) 132 15.2% Lys (K) 85 9.8% Met (M) 11 1.3% Phe (F) 30 3.5% Pro (P) 15 1.7% Ser (S) 65 7.5% Thr (T) 45 5.2% Trp (W) 4 0.5% Tyr (Y) 23 2.6% Val (V) 33 3.8% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 133 Total number of positively charged residues (Arg + Lys): 116 Atomic composition: Carbon C 4457 Hydrogen H 7225 Nitrogen N 1195 Oxygen O 1383 Sulfur S 19 Formula: C4457H7225N1195O1383S19 Total number of atoms: 14279 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 56770 Abs 0.1% (=1 g/l) 0.566, assuming all pairs of Cys residues form cystines Ext. coefficient 56270 Abs 0.1% (=1 g/l) 0.561, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 43.63 This classifies the protein as unstable. Aliphatic index: 103.56 Grand average of hydropathicity (GRAVY): -0.484