ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MRPAAATAPK WLLLALSALL PLWPTAKSWE LTILHTNDVH SRLEQTSDDS TKCLNASLCV 

        70         80         90        100        110        120 
GGVARLFTKV QQIRKEEPNV LLLDAGDQYQ GTIWFTVYKG LEVAHFMNLL GYDAMALGNH 

       130        140        150        160        170        180 
EFDNGVEGLI DPLLRNVKFP ILSANIKARG PLAPQISGLY LPYKVLSVGG EVVGIVGYTS 

       190        200        210        220        230        240 
KETPFLSNPG TNLVFEDEVT ALQPEVDKLK TLNVNKIIAL GHSGFEMDKL IAQKVRGVDV 

       250        260        270        280        290        300 
VVGGHTNTFL YTGNPPSKEV PAGKYPFIVT SDDGRKVPVV QAYAFGKYLG YLKVEFDDKG 

       310        320        330        340        350        360 
NVVTSYGNPI LLNSTIREDA AIKADINQWR IKLDNYSTQE LGRTIVYLNG SAQECRFREC 

       370        380        390        400        410        420 
NMGNLICDAM INNNLRHPDE MFWNHVSMCI VNGGGIRSPI DERNNGTITW ENLAAVLPFG 

       430        440        450        460        470        480 
GTFDLVQLKG STLKKAFEHS VHRYGQSTGE FLQVGGIHVV YDISRKPWDR VVQLKVLCTK 

       490        500        510        520        530        540 
CRVPIYEPLE MDKVYKVVLP SYLVNGGDGF QMIKDELLKH DSGDQDISVV SEYISKMKVI 

       550        560        570 
YPAVEGRIKF SAASHYQGSF PLIILSFWAV ILVLYQ 

References and documentation are available.

Number of amino acids: 576

Molecular weight: 63950.65

Theoretical pI: 6.51

Amino acid composition: 
Ala (A)  34	  5.9%
Arg (R)  21	  3.6%
Asn (N)  31	  5.4%
Asp (D)  31	  5.4%
Cys (C)   8	  1.4%
Gln (Q)  20	  3.5%
Glu (E)  29	  5.0%
Gly (G)  48	  8.3%
His (H)  13	  2.3%
Ile (I)  35	  6.1%
Leu (L)  62	 10.8%
Lys (K)  36	  6.2%
Met (M)  11	  1.9%
Phe (F)  22	  3.8%
Pro (P)  28	  4.9%
Ser (S)  33	  5.7%
Thr (T)  28	  4.9%
Trp (W)   9	  1.6%
Tyr (Y)  23	  4.0%
Val (V)  54	  9.4%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 60
Total number of positively charged residues (Arg + Lys): 57

Atomic composition:

Carbon      C	      2897
Hydrogen    H	      4539
Nitrogen    N	       761
Oxygen      O	       832
Sulfur      S	        19

Formula: C2897H4539N761O832S19
Total number of atoms: 9048

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    84270
Abs 0.1% (=1 g/l)   1.318, assuming all pairs of Cys residues form cystines


Ext. coefficient    83770
Abs 0.1% (=1 g/l)   1.310, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 24.22
This classifies the protein as stable.



Aliphatic index: 98.77

Grand average of hydropathicity (GRAVY): -0.051