ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MRQAGIFSHL KNFWKIILQF SKLKKKHIVM SSENQKIVVF GSIVQDLVSY TDSFPRPGES 

        70         80         90        100        110        120 
VRGHNFKLGS GGKGANQAVA AARLGINVSM IGMVGEDMFG DSNIKDLSSN GVDTSCVGRT 

       130        140        150        160        170        180 
KKTHTATATI TVNKEGENNI VVTLGANLEM SPEIADANSS KIAGSKMVIC QGEIDEKGNR 

       190        200        210        220        230        240 
RAFEIARSHG VTTFLNPAPG DPNMDKTILE LVDIICTNEN EAEFITGIAQ NNVKDAEKAA 

       250        260        270        280        290        300 
RAMLKMGPQH AIITLGGKGV LLASKGVDDV EHTAVIKVDA VDTTGAGDCF CGSLAAHLVA 

       310        320        330        340 
GHPISASIRS AANLAALSVT RHGTQSSYWK LDEIRQQYPE FLP 

References and documentation are available.

Number of amino acids: 343

Molecular weight: 36591.71

Theoretical pI: 7.15

Amino acid composition: 
Ala (A)  34	  9.9%
Arg (R)  12	  3.5%
Asn (N)  20	  5.8%
Asp (D)  18	  5.2%
Cys (C)   5	  1.5%
Gln (Q)  11	  3.2%
Glu (E)  18	  5.2%
Gly (G)  32	  9.3%
His (H)  10	  2.9%
Ile (I)  27	  7.9%
Leu (L)  22	  6.4%
Lys (K)  24	  7.0%
Met (M)  10	  2.9%
Phe (F)  12	  3.5%
Pro (P)  10	  2.9%
Ser (S)  27	  7.9%
Thr (T)  20	  5.8%
Trp (W)   2	  0.6%
Tyr (Y)   3	  0.9%
Val (V)  26	  7.6%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 36
Total number of positively charged residues (Arg + Lys): 36

Atomic composition:

Carbon      C	      1596
Hydrogen    H	      2582
Nitrogen    N	       456
Oxygen      O	       497
Sulfur      S	        15

Formula: C1596H2582N456O497S15
Total number of atoms: 5146

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    15720
Abs 0.1% (=1 g/l)   0.430, assuming all pairs of Cys residues form cystines


Ext. coefficient    15470
Abs 0.1% (=1 g/l)   0.423, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 26.02
This classifies the protein as stable.



Aliphatic index: 87.61

Grand average of hydropathicity (GRAVY): -0.127