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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MRQRVGRSIA RAKFINTALL GRKRPVMERV VDIAHVDSSK AIQPLMKELE TDTTEARYKV

70 80 90 100 110 120
LQSVLEIYDD EKNIEPALTK EFHKMYLDVA FEISLPPQMT ALDASQPWML YWIANSLKVM

130 140 150 160 170 180
DRDWLSDDTK RKIVDKLFTI SPSGGPFGGG PGQLSHLAST YAAINALSLC DNIDGCWDRI

190 200 210 220 230 240
DRKGIYQWLI SLKEPNGGFK TCLEVGEVDT RGIYCALSIA TLLNILTEEL TEGVLNYLKN

250 260 270 280 290 300
CQNYEGGFGS CPHVDEAHGG YTFCATASLA ILRSMDQINV EKLLEWSSAR QLQEERGFCG

310 320 330 340 350 360
RSNKLVDGCY SFWVGGSAAI LEAFGYGQCF NKHALRDYIL YCCQEKEQPG LRDKPGAHSD

370 380 390 400 410 420
FYHTNYCLLG LAVAESSYSC TPNDSPHNIK CTPDRLIGSS KLTDVNPVYG LPIENVRKII

430
HYFKSNLSSP S


References and documentation are available.

Number of amino acids: 431 Molecular weight: 48189.94 Theoretical pI: 5.97
Amino acid composition: 
Ala (A) 29 6.7% Arg (R) 21 4.9% Asn (N) 19 4.4% Asp (D) 26 6.0% Cys (C) 15 3.5% Gln (Q) 14 3.2% Glu (E) 26 6.0% Gly (G) 32 7.4% His (H) 10 2.3% Ile (I) 27 6.3% Leu (L) 45 10.4% Lys (K) 25 5.8% Met (M) 8 1.9% Phe (F) 14 3.2% Pro (P) 19 4.4% Ser (S) 34 7.9% Thr (T) 20 4.6% Trp (W) 7 1.6% Tyr (Y) 19 4.4% Val (V) 21 4.9% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 52 Total number of positively charged residues (Arg + Lys): 46 Atomic composition: Carbon C 2140 Hydrogen H 3341 Nitrogen N 579 Oxygen O 642 Sulfur S 23 Formula: C2140H3341N579O642S23 Total number of atoms: 6725 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 67685 Abs 0.1% (=1 g/l) 1.405, assuming all pairs of Cys residues form cystines Ext. coefficient 66810 Abs 0.1% (=1 g/l) 1.386, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 47.14 This classifies the protein as unstable. Aliphatic index: 86.01 Grand average of hydropathicity (GRAVY): -0.260