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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MRQVLQKDKR DVQLSKALSY LLRHTAVKEK LTIDSNGYTP LKELLSHNRL KTHKCTVDDI

70 80 90 100 110 120
HRIVKENDKQ RFHIKTLGAD EEWICATQGH SIKSIQPSDE VLVPITEASQ LPQELIHGTN

130 140 150 160 170 180
LQSVIKIIES GAISPMSRNH VHLSPGMLHA KGVISGMRSS SNVYIFIDCH SPLFFQTLKM

190 200 210 220 230
FRSLNNVYLS SSIPVELIQK VVVKGNLKDE EKLDTLRRIL HERNIPLEKI


References and documentation are available.

Number of amino acids: 230 Molecular weight: 26196.41 Theoretical pI: 9.30
Amino acid composition: 
Ala (A) 7 3.0% Arg (R) 12 5.2% Asn (N) 10 4.3% Asp (D) 11 4.8% Cys (C) 3 1.3% Gln (Q) 11 4.8% Glu (E) 14 6.1% Gly (G) 9 3.9% His (H) 12 5.2% Ile (I) 21 9.1% Leu (L) 27 11.7% Lys (K) 20 8.7% Met (M) 5 2.2% Phe (F) 5 2.2% Pro (P) 9 3.9% Ser (S) 22 9.6% Thr (T) 11 4.8% Trp (W) 1 0.4% Tyr (Y) 4 1.7% Val (V) 16 7.0% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 25 Total number of positively charged residues (Arg + Lys): 32 Atomic composition: Carbon C 1161 Hydrogen H 1906 Nitrogen N 332 Oxygen O 339 Sulfur S 8 Formula: C1161H1906N332O339S8 Total number of atoms: 3746 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 11585 Abs 0.1% (=1 g/l) 0.442, assuming all pairs of Cys residues form cystines Ext. coefficient 11460 Abs 0.1% (=1 g/l) 0.437, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 49.88 This classifies the protein as unstable. Aliphatic index: 104.61 Grand average of hydropathicity (GRAVY): -0.317