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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MRRLLTGCLL SSARPLKSRL PLLMSSSLPS SAGKKPKQAT LARFFTSMKN KPTEGTPSPK

70 80 90 100 110 120
KSSKHMLEDR MDNVSGEEEY ATKKLKQTAV THTVAAPSSM GSNFSSIPSS APSSGVADSP

130 140 150 160 170 180
QQSQRLVGEV EDALSSNNND HYSSNIPYSE VCEVFNKIEA ISSRLEIIRI CSDFFIKIMK

190 200 210 220 230 240
QSSKNLIPTT YLFINRLGPD YEAGLELGLG ENLLMKTISE TCGKSMSQIK LKYKDIGDLG

250 260 270 280 290 300
EIAMGARNVQ PTMFKPKPLT VGEVFKNLRA IAKTQGKDSQ LKKMKLIKRM LTACKGIEAK

310 320 330 340 350 360
FLIRSLESKL RIGLAEKTVL ISLSKALLLH DENREDSPDK DVPMDVLESA QQKIRDAFCQ

370 380 390 400 410 420
VPNYEIVINS CLEHGIMNLD KYCTLRPGIP LKPMLAKPTK AINEVLDRFQ GETFTSEYKY

430 440 450 460 470 480
DGERAQVHLL NDGTMRIYSR NGENMTERYP EINITDFIQD LDTTKNLILD CEAVAWDKDQ

490 500 510 520 530 540
GKILPFQVLS TRKRKDVELN DVKVKVCLFA FDILCYNDER LINKSLKERR EYLTKVTKVV

550 560 570 580 590 600
PGEFQYATQI TTNNLDELQK FLDESVNHSC EGLMVKMLEG PESHYEPSKR SRNWLKLKKD

610 620 630 640 650 660
YLEGVGDSLD LCVLGAYYGR GKRTGTYGGF LLGCYNQDTG EFETCCKIGT GFSDEMLQLL

670 680 690 700 710 720
HDRLTPTIID GPKATFVFDS SAEPDVWFEP TTLFEVLTAD LSLSPIYKAG SATFDKGVSL

730 740 750
RFPRFLRIRE DKGVEDATSS DQIVELYENQ SHMQN


References and documentation are available.

Number of amino acids: 755 Molecular weight: 84828.28 Theoretical pI: 7.44
Amino acid composition: 
Ala (A) 37 4.9% Arg (R) 37 4.9% Asn (N) 33 4.4% Asp (D) 46 6.1% Cys (C) 16 2.1% Gln (Q) 26 3.4% Glu (E) 55 7.3% Gly (G) 45 6.0% His (H) 10 1.3% Ile (I) 42 5.6% Leu (L) 83 11.0% Lys (K) 65 8.6% Met (M) 22 2.9% Phe (F) 29 3.8% Pro (P) 35 4.6% Ser (S) 65 8.6% Thr (T) 46 6.1% Trp (W) 3 0.4% Tyr (Y) 23 3.0% Val (V) 37 4.9% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 101 Total number of positively charged residues (Arg + Lys): 102 Atomic composition: Carbon C 3742 Hydrogen H 6013 Nitrogen N 1013 Oxygen O 1151 Sulfur S 38 Formula: C3742H6013N1013O1151S38 Total number of atoms: 11957 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 51770 Abs 0.1% (=1 g/l) 0.610, assuming all pairs of Cys residues form cystines Ext. coefficient 50770 Abs 0.1% (=1 g/l) 0.599, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 40.42 This classifies the protein as unstable. Aliphatic index: 83.68 Grand average of hydropathicity (GRAVY): -0.415