ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MRRRRVLLLL LSTTTFLRVS TAQQDEPKAS VVEVQTKLGT VRGTESDHGN KRVRSFLGVP 

        70         80         90        100        110        120 
FAEPPINEHR FKKPTPARPW NGTISANTLS PACFQGRDSY DPTFWGSEMW NANTPVSEDC 

       130        140        150        160        170        180 
LYVNIWAPAD AYNLTVLVWL FGGGFWYGSP SLLLYDGKEL ATRGNVIVVN INYRVGPFGY 

       190        200        210        220        230        240 
LFLDHEDVPG NMGMLDQQLA LYWIRDHIFS FGGNPARISL VGESAGAASI VAHLIAPASK 

       250        260        270        280        290        300 
GLFQNGILQS GSLDNKWSMD SPKRAKQKST ALADLVGCNQ TKITDQTACL RNTPAQLLID 

       310        320        330        340        350        360 
NIWNVGLNFL EFPFAIVSKD QNFFKHLDGF IALREGTYST DVNLMFGINH DEGNFWNIYN 

       370        380        390        400        410        420 
LAKFFDKQSV KPGLDRDEFH ECVDTAFAVQ PELVRTAAKY VYSDPKCTDP KKKTDFYTEQ 

       430        440        450        460        470        480 
VNQMVGDYFF TCDSIWFAHN YPKMAGNQSN VFVYYFDQPS SANPWPKWTG VMHGYEIEYV 

       490        500        510        520        530        540 
FGVPLHNTTA GYTKEEMDVS EKVIDFWTTF ANTGVPSLRK RAVGTTQKIK WDRYDGTDHT 

       550        560        570        580        590        600 
TWMNIKTGSF RMIQEIKKVE CDLWRNAKDM EYSAYKEELA TTSSSTLTQY TIYLILLSAF 


QLVFNFF 

References and documentation are available.

Number of amino acids: 607

Molecular weight: 68833.98

Theoretical pI: 6.21

Amino acid composition: 
Ala (A)  41	  6.8%
Arg (R)  25	  4.1%
Asn (N)  36	  5.9%
Asp (D)  37	  6.1%
Cys (C)   8	  1.3%
Gln (Q)  23	  3.8%
Glu (E)  27	  4.4%
Gly (G)  41	  6.8%
His (H)  12	  2.0%
Ile (I)  27	  4.4%
Leu (L)  49	  8.1%
Lys (K)  34	  5.6%
Met (M)  13	  2.1%
Phe (F)  39	  6.4%
Pro (P)  29	  4.8%
Ser (S)  38	  6.3%
Thr (T)  45	  7.4%
Trp (W)  17	  2.8%
Tyr (Y)  25	  4.1%
Val (V)  41	  6.8%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 64
Total number of positively charged residues (Arg + Lys): 59

Atomic composition:

Carbon      C	      3125
Hydrogen    H	      4712
Nitrogen    N	       816
Oxygen      O	       903
Sulfur      S	        21

Formula: C3125H4712N816O903S21
Total number of atoms: 9577

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient   131250
Abs 0.1% (=1 g/l)   1.907, assuming all pairs of Cys residues form cystines


Ext. coefficient   130750
Abs 0.1% (=1 g/l)   1.899, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 43.03
This classifies the protein as unstable.



Aliphatic index: 75.17

Grand average of hydropathicity (GRAVY): -0.295