ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MRTDWNFFFC ILLQAIFVVG TQTSRTLVLY DQSTEPLEEY SVYLKDLEQR NYKLEYLDIN 

        70         80         90        100        110        120 
STSTTVDLYD KEQRLFDNII VFPTKGGKNL ARQIPVKQLI KFFENEGNIL CMSSPGAVPN 

       130        140        150        160        170        180 
TIRLFLNELG IYPSPKGHVI RDYFSPSSEE LVVSSNHLLN KYVYNARKSE DFVFGESSAA 

       190        200        210        220        230        240 
LLENREQIVP ILNAPRTSFT ESKGKCNSWT SGSQGFLVVG FQNLNNARLV WIGSSDFLKN 

       250        260        270        280        290        300 
KNQDSNQEFA KELLKWTFNE KSVIKSVHAV HSHADGTSYD EEPYKIKDKV IYSVGFSEWN 

       310        320        330        340        350        360 
GEEWLPHIAD DIQFELRQVD PYYRLTLSPS GNDSETQYYT TGEFILPDRH GVFTFLTDYR 

       370        380        390        400        410        420 
KIGLSFTTDK DVKAIRHLAN DEYPRSWEIS NSWVYISAIC GVIVAWIFFV VSFVTTSSVG 

       430 
KKLETFKKTN 

References and documentation are available.

Number of amino acids: 430

Molecular weight: 49391.71

Theoretical pI: 5.62

Amino acid composition: 
Ala (A)  16	  3.7%
Arg (R)  17	  4.0%
Asn (N)  27	  6.3%
Asp (D)  23	  5.3%
Cys (C)   4	  0.9%
Gln (Q)  15	  3.5%
Glu (E)  30	  7.0%
Gly (G)  22	  5.1%
His (H)   8	  1.9%
Ile (I)  27	  6.3%
Leu (L)  38	  8.8%
Lys (K)  28	  6.5%
Met (M)   2	  0.5%
Phe (F)  28	  6.5%
Pro (P)  16	  3.7%
Ser (S)  41	  9.5%
Thr (T)  27	  6.3%
Trp (W)   9	  2.1%
Tyr (Y)  20	  4.7%
Val (V)  32	  7.4%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 53
Total number of positively charged residues (Arg + Lys): 45

Atomic composition:

Carbon      C	      2249
Hydrogen    H	      3420
Nitrogen    N	       576
Oxygen      O	       667
Sulfur      S	         6

Formula: C2249H3420N576O667S6
Total number of atoms: 6918

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    79550
Abs 0.1% (=1 g/l)   1.611, assuming all pairs of Cys residues form cystines


Ext. coefficient    79300
Abs 0.1% (=1 g/l)   1.606, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 36.25
This classifies the protein as stable.



Aliphatic index: 84.26

Grand average of hydropathicity (GRAVY): -0.332