ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MRTLLLTILI FFFTVNPISA KFYTNVSSIP PLQFLNATQN AWETFSKLAG CHIGENINGL 

        70         80         90        100        110        120 
SKLKQYFRRF GYITTTGNCT DDFDDVLQSA INTYQKNFNL KVTGKLDSST LRQIVKPRCG 

       130        140        150        160        170        180 
NPDLIDGVSE MNGGKILRTT EKYSFFPGKP RWPKRKRDLT YAFAPQNNLT DEVKRVFSRA 

       190        200        210        220        230        240 
FTRWAEVTPL NFTRSESILR ADIVIGFFSG EHGDGEPFDG AMGTLAHASS PPTGMLHLDG 

       250        260        270        280        290        300 
DEDWLISNGE ISRRILPVTT VVDLESVAVH EIGHLLGLGH SSVEDAIMFP AISGGDRKVE 

       310        320        330        340        350        360 
LAKDDIEGIQ HLYGGNPNGD GGGSKPSRES QSTGGDSVRR WRGWMISLSS IATCIFLISV 

References and documentation are available.

Number of amino acids: 360

Molecular weight: 39760.07

Theoretical pI: 6.72

Amino acid composition: 
Ala (A)  18	  5.0%
Arg (R)  21	  5.8%
Asn (N)  18	  5.0%
Asp (D)  22	  6.1%
Cys (C)   4	  1.1%
Gln (Q)   9	  2.5%
Glu (E)  17	  4.7%
Gly (G)  35	  9.7%
His (H)   8	  2.2%
Ile (I)  26	  7.2%
Leu (L)  32	  8.9%
Lys (K)  17	  4.7%
Met (M)   6	  1.7%
Phe (F)  21	  5.8%
Pro (P)  17	  4.7%
Ser (S)  31	  8.6%
Thr (T)  26	  7.2%
Trp (W)   6	  1.7%
Tyr (Y)   7	  1.9%
Val (V)  19	  5.3%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 39
Total number of positively charged residues (Arg + Lys): 38

Atomic composition:

Carbon      C	      1775
Hydrogen    H	      2769
Nitrogen    N	       489
Oxygen      O	       530
Sulfur      S	        10

Formula: C1775H2769N489O530S10
Total number of atoms: 5573

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    43680
Abs 0.1% (=1 g/l)   1.099, assuming all pairs of Cys residues form cystines


Ext. coefficient    43430
Abs 0.1% (=1 g/l)   1.092, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 47.04
This classifies the protein as unstable.



Aliphatic index: 83.14

Grand average of hydropathicity (GRAVY): -0.236