ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MRVSQSLVPF AIIALVLSFV NAYDPSPLQD FCVAIDDLKG VFVNGRFCKD PKRVDAKDFF 

        70         80         90        100        110        120 
FSGLNVPGNT NNQVGSNVTT VNVDQIPGLN TMGISLVRID YAPHGQNPPH THPRGSEILV 

       130        140        150        160        170        180 
LVEGTLYVGF VSSNQDNNRL FAKVLHPGDV FVFPIGMIHF QVNVGKIPAV AFAGLSSQNA 

       190        200        210        220 
GVITIANTVF GSNPPIYPEL LARAFQLDAS VVKELQAKFG SI 

References and documentation are available.

Number of amino acids: 222

Molecular weight: 23925.47

Theoretical pI: 6.50

Amino acid composition: 
Ala (A)  16	  7.2%
Arg (R)   7	  3.2%
Asn (N)  17	  7.7%
Asp (D)  12	  5.4%
Cys (C)   2	  0.9%
Gln (Q)  10	  4.5%
Glu (E)   4	  1.8%
Gly (G)  18	  8.1%
His (H)   5	  2.3%
Ile (I)  14	  6.3%
Leu (L)  18	  8.1%
Lys (K)   8	  3.6%
Met (M)   3	  1.4%
Phe (F)  17	  7.7%
Pro (P)  16	  7.2%
Ser (S)  15	  6.8%
Thr (T)   8	  3.6%
Trp (W)   0	  0.0%
Tyr (Y)   4	  1.8%
Val (V)  28	 12.6%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 16
Total number of positively charged residues (Arg + Lys): 15

Atomic composition:

Carbon      C	      1089
Hydrogen    H	      1694
Nitrogen    N	       288
Oxygen      O	       309
Sulfur      S	         5

Formula: C1089H1694N288O309S5
Total number of atoms: 3385

Extinction coefficients:

This protein does not contain any Trp residues. Experience shows that
this could result in more than 10% error in the computed extinction coefficient.

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient     6085
Abs 0.1% (=1 g/l)   0.254, assuming all pairs of Cys residues form cystines


Ext. coefficient     5960
Abs 0.1% (=1 g/l)   0.249, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 23.90
This classifies the protein as stable.



Aliphatic index: 100.00

Grand average of hydropathicity (GRAVY): 0.231