ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSADETDAKF HPLETDLQSD TAAATSTAAA SRSPSLQEKP IEMPLDMGKA PSPRGEDQRV 

        70         80         90        100        110        120 
TNEEDLFLFN RLRASQNRVM DSLEPQQQSQ YTSSSVSTME PSADFTSFSA VTTLPPPPHQ 

       130        140        150        160        170        180 
QQQQQQQQQQ QQQLVVQAQY TQNQPNLQSD VLGTAIAEQP FYVNAKQYYR ILKRRYARAK 

       190        200        210        220        230        240 
LEEKLRISRE RKPYLHESRH KHAMRRPRGE GGRFLTAAEI KAMKSKKSGA SDDPDDSHED 

       250        260 
KKITTKIIQE QPHATSTAAA ADKKT 

References and documentation are available.

Number of amino acids: 265

Molecular weight: 29867.17

Theoretical pI: 8.63

Amino acid composition: 
Ala (A)  28	 10.6%
Arg (R)  18	  6.8%
Asn (N)   6	  2.3%
Asp (D)  16	  6.0%
Cys (C)   0	  0.0%
Gln (Q)  31	 11.7%
Glu (E)  18	  6.8%
Gly (G)   7	  2.6%
His (H)   7	  2.6%
Ile (I)   8	  3.0%
Leu (L)  17	  6.4%
Lys (K)  18	  6.8%
Met (M)   7	  2.6%
Phe (F)   7	  2.6%
Pro (P)  18	  6.8%
Ser (S)  25	  9.4%
Thr (T)  19	  7.2%
Trp (W)   0	  0.0%
Tyr (Y)   7	  2.6%
Val (V)   8	  3.0%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 34
Total number of positively charged residues (Arg + Lys): 36

Atomic composition:

Carbon      C	      1281
Hydrogen    H	      2054
Nitrogen    N	       388
Oxygen      O	       422
Sulfur      S	         7

Formula: C1281H2054N388O422S7
Total number of atoms: 4152

Extinction coefficients:

This protein does not contain any Trp residues. Experience shows that
this could result in more than 10% error in the computed extinction coefficient.

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    10430
Abs 0.1% (=1 g/l)   0.349

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 67.40
This classifies the protein as unstable.



Aliphatic index: 56.11

Grand average of hydropathicity (GRAVY): -1.051