ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSAETAAANT ATAPVPEVQE QESSKSKQVN LTPAPLPTSS PWKLAPTEIP VSTISIEDLD 

        70         80         90        100        110        120 
ATRKKKNRTP TPKSSTATKW VPIKASITVS GTKRSGSKNG ASNGNSNKSK NNKTAASSTS 

       130        140        150        160        170        180 
SSNANRKKKH HQHNAKKQQQ MKKDGFESAV GEEDSKDATS QENGQSTQQQ QPPHHRNHHH 

       190        200        210        220        230        240 
SHHHNSNGPQ RRKFHNSNNA GMPQNQGFPP QFKPYQGRNA RNNNNNRSKY HNHFHHNQQH 

       250        260        270        280        290        300 
PQQPMVKLQQ QFYPVQPVLM AINNIARQIE YYFSEENLTV DNYLRSKLSK DGFAPLSLIS 

       310        320        330        340        350        360 
KFYRVVNMSF GGDTNLILAA LREIVANEAA TVNVAEGTLA AKEGDNVTGE AKEPSPLDKY 

       370        380        390        400        410        420 
FVRSKSWSNW LPETFETEIN IEKELVGDAL DQFMISLPPV PQQEEESSTE LASQEQETKE 

       430 
DSAPVAAGES ESSL 

References and documentation are available.

Number of amino acids: 434

Molecular weight: 48059.94

Theoretical pI: 8.88

Amino acid composition: 
Ala (A)  37	  8.5%
Arg (R)  15	  3.5%
Asn (N)  39	  9.0%
Asp (D)  13	  3.0%
Cys (C)   0	  0.0%
Gln (Q)  32	  7.4%
Glu (E)  33	  7.6%
Gly (G)  19	  4.4%
His (H)  17	  3.9%
Ile (I)  14	  3.2%
Leu (L)  22	  5.1%
Lys (K)  35	  8.1%
Met (M)   7	  1.6%
Phe (F)  13	  3.0%
Pro (P)  30	  6.9%
Ser (S)  48	 11.1%
Thr (T)  27	  6.2%
Trp (W)   4	  0.9%
Tyr (Y)   8	  1.8%
Val (V)  21	  4.8%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 46
Total number of positively charged residues (Arg + Lys): 50

Atomic composition:

Carbon      C	      2075
Hydrogen    H	      3265
Nitrogen    N	       623
Oxygen      O	       681
Sulfur      S	         7

Formula: C2075H3265N623O681S7
Total number of atoms: 6651

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    33920
Abs 0.1% (=1 g/l)   0.706

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 68.32
This classifies the protein as unstable.



Aliphatic index: 54.91

Grand average of hydropathicity (GRAVY): -1.022