ProtParam
User-provided sequence:
10 20 30 40 50 60
MSAGDISAIN IKSVKKNRRR KKRRTADVSS SDSSSSDPSS ESEKEEIQNG AIEEHVGENG
70 80 90 100 110 120
KSDHVFSKGN DEDKQEDIAI EVSDVELTDE ESKDLKLNSK EVIDDLTKIS LSKIPEPTKS
130 140 150 160 170 180
QNKEGFMNAS KIAENIKLAR EEYNELAENF VPKGKDKTKL REEYLNLLFE NYGDDINRLR
190 200 210 220
AAPDFTNKSL SILADALQEG IGMFDIGELE LVLKNKEMEN
References and
documentation are available.
Number of amino acids: 220
Molecular weight: 24656.31
Theoretical pI: 4.79
Total number of negatively charged residues (Asp + Glu): 48
Total number of positively charged residues (Arg + Lys): 34
Atomic composition:
Carbon C 1057
Hydrogen H 1723
Nitrogen N 297
Oxygen O 371
Sulfur S 4
Formula: C
1057H
1723N
297O
371S
4
Total number of atoms: 3452
Extinction coefficients:
This protein does not contain any Trp residues. Experience shows that
this could result in more than 10% error in the computed extinction coefficient.
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 4470
Abs 0.1% (=1 g/l) 0.181
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 51.21
This classifies the protein as unstable.
Aliphatic index: 78.05
Grand average of hydropathicity (GRAVY): -0.907