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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSAIKEVKSE LRQFMKTLLG KISKEETQRQ TEAVFEKIIE SKWFQESKRL SVYVSTSGEI

70 80 90 100 110 120
QTDSIIQKAL EMGKEVFIPQ FTKGSTAMDM VRVPDQTAFD NLPSTLWGIR QPEPKWKWQS

130 140 150 160 170 180
YHETGPLDLI LAPGVAFSPY GLRCGHGKGY YDRFFSTHHK HFPENSPKKI GLALREQIIG

190 200
TIPISETDVE LDEVIYEGET IIFDTI


References and documentation are available.

Number of amino acids: 206 Molecular weight: 23560.94 Theoretical pI: 5.79
Amino acid composition: 
Ala (A) 8 3.9% Arg (R) 8 3.9% Asn (N) 2 1.0% Asp (D) 9 4.4% Cys (C) 1 0.5% Gln (Q) 11 5.3% Glu (E) 20 9.7% Gly (G) 14 6.8% His (H) 5 2.4% Ile (I) 19 9.2% Leu (L) 14 6.8% Lys (K) 17 8.3% Met (M) 5 2.4% Phe (F) 11 5.3% Pro (P) 11 5.3% Ser (S) 16 7.8% Thr (T) 15 7.3% Trp (W) 4 1.9% Tyr (Y) 6 2.9% Val (V) 10 4.9% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 29 Total number of positively charged residues (Arg + Lys): 25 Atomic composition: Carbon C 1067 Hydrogen H 1662 Nitrogen N 274 Oxygen O 315 Sulfur S 6 Formula: C1067H1662N274O315S6 Total number of atoms: 3324 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 30940 Abs 0.1% (=1 g/l) 1.313, assuming all pairs of Cys residues form cystines Ext. coefficient 30940 Abs 0.1% (=1 g/l) 1.313, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 42.03 This classifies the protein as unstable. Aliphatic index: 80.44 Grand average of hydropathicity (GRAVY): -0.414