ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSANSKDRNQ SNQDAKRQQQ NFPKKISEGE ADLYLDQYNF TTTAAIVSSV DRKIFVLLRD 

        70         80         90        100        110        120 
GRMLFGVLRT FDQYANLILQ DCVERIYFSE ENKYAEEDRG IFMIRGENVV MLGEVDIDKE 

       130        140        150        160        170 
DQPLEAMERI PFKEAWLTKQ KNDEKRFKEE THKGKKMARH GIVYDFHKSD MY 

References and documentation are available.

Number of amino acids: 172

Molecular weight: 20306.94

Theoretical pI: 5.72

Amino acid composition: 
Ala (A)  10	  5.8%
Arg (R)  12	  7.0%
Asn (N)   9	  5.2%
Asp (D)  15	  8.7%
Cys (C)   1	  0.6%
Gln (Q)  10	  5.8%
Glu (E)  16	  9.3%
Gly (G)   8	  4.7%
His (H)   3	  1.7%
Ile (I)  10	  5.8%
Leu (L)  11	  6.4%
Lys (K)  16	  9.3%
Met (M)   7	  4.1%
Phe (F)  10	  5.8%
Pro (P)   3	  1.7%
Ser (S)   8	  4.7%
Thr (T)   6	  3.5%
Trp (W)   1	  0.6%
Tyr (Y)   7	  4.1%
Val (V)   9	  5.2%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 31
Total number of positively charged residues (Arg + Lys): 28

Atomic composition:

Carbon      C	       894
Hydrogen    H	      1400
Nitrogen    N	       250
Oxygen      O	       275
Sulfur      S	         8

Formula: C894H1400N250O275S8
Total number of atoms: 2827

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    15930
Abs 0.1% (=1 g/l)   0.784, assuming all pairs of Cys residues form cystines


Ext. coefficient    15930
Abs 0.1% (=1 g/l)   0.784, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 44.32
This classifies the protein as unstable.



Aliphatic index: 68.60

Grand average of hydropathicity (GRAVY): -0.833