ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSASIPETMK AVVIENGKAV VKQDIPIPEL EEGFVLIKTV AVAGNPTDWK HIDFKIGPQG 

        70         80         90        100        110        120 
ALLGCDAAGQ IVKLGPNVDA ARFAIGDYIY GVIHGASVRF PSNGAFAEYS AISSETAYKP 

       130        140        150        160        170        180 
AREFRLCGKD KLPEGPVKSL EGAVSLPVSL TTAGMILTHS FGLDMTWKPS KAQRDQPILF 

       190        200        210        220        230        240 
WGGATAVGQM LIQLAKKLNG FSKIIVVASR KHEKLLKEYG ADELFDYHDA DVIEQIKKKY 

       250        260        270        280        290        300 
NNIPYLVDCV SNTETIQQVY KCAADDLDAT VVQLTVLTEK DIKEEDRRQN VSIEGTLLYL 

       310        320        330        340        350        360 
IGGNDVPFGT FTLPADPEYK EAAIKFIKFI NPKINDGEIH HIPVKVYKNG LDDIPQLLDD 

       370 
IKHGRNSGEK LVAVLK 

References and documentation are available.

Number of amino acids: 376

Molecular weight: 41164.39

Theoretical pI: 5.83

Amino acid composition: 
Ala (A)  33	  8.8%
Arg (R)   9	  2.4%
Asn (N)  14	  3.7%
Asp (D)  26	  6.9%
Cys (C)   4	  1.1%
Gln (Q)  13	  3.5%
Glu (E)  23	  6.1%
Gly (G)  30	  8.0%
His (H)   8	  2.1%
Ile (I)  32	  8.5%
Leu (L)  32	  8.5%
Lys (K)  34	  9.0%
Met (M)   5	  1.3%
Phe (F)  14	  3.7%
Pro (P)  20	  5.3%
Ser (S)  17	  4.5%
Thr (T)  17	  4.5%
Trp (W)   3	  0.8%
Tyr (Y)  12	  3.2%
Val (V)  30	  8.0%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 49
Total number of positively charged residues (Arg + Lys): 43

Atomic composition:

Carbon      C	      1862
Hydrogen    H	      2955
Nitrogen    N	       483
Oxygen      O	       548
Sulfur      S	         9

Formula: C1862H2955N483O548S9
Total number of atoms: 5857

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    34630
Abs 0.1% (=1 g/l)   0.841, assuming all pairs of Cys residues form cystines


Ext. coefficient    34380
Abs 0.1% (=1 g/l)   0.835, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 25.82
This classifies the protein as stable.



Aliphatic index: 98.30

Grand average of hydropathicity (GRAVY): -0.114