ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSAVNVAPEL INADNTITYD AIVIGAGVIG PCVATGLARK GKKVLIVERD WAMPDRIVGE 

        70         80         90        100        110        120 
LMQPGGVRAL RSLGMIQSIN NIEAYPVTGY TVFFNGEQVD IPYPYKADIP KVEKLKDLVK 

       130        140        150        160        170        180 
DGNDKVLEDS TIHIKDYEDD ERERGVAFVH GRFLNNLRNI TAQEPNVTRV QGNCIEILKD 

       190        200        210        220        230        240 
EKNEVVGAKV DIDGRGKVEF KAHLTFICDG IFSRFRKELH PDHVPTVGSS FVGMSLFNAK 

       250        260        270        280        290        300 
NPAPMHGHVI LGSDHMPILV YQISPEETRI LCAYNSPKVP ADIKSWMIKD VQPFIPKSLR 

       310        320        330        340        350        360 
PSFDEAVSQG KFRAMPNSYL PARQNDVTGM CVIGDALNMR HPLTGGGMTV GLHDVVLLIK 

       370        380        390        400        410        420 
KIGDLDFSDR EKVLDELLDY HFERKSYDSV INVLSVALYS LFAADSDNLK ALQKGCFKYF 

       430        440        450        460        470        480 
QRGGDCVNKP VEFLSGVLPK PLQLTRVFFA VAFYTIYLNM EERGFLGLPM ALLEGIMILI 

       490 
TAIRVFTPFL FGELIG 

References and documentation are available.

Number of amino acids: 496

Molecular weight: 55125.88

Theoretical pI: 6.04

Amino acid composition: 
Ala (A)  31	  6.2%
Arg (R)  24	  4.8%
Asn (N)  23	  4.6%
Asp (D)  34	  6.9%
Cys (C)   7	  1.4%
Gln (Q)  12	  2.4%
Glu (E)  27	  5.4%
Gly (G)  40	  8.1%
His (H)  11	  2.2%
Ile (I)  37	  7.5%
Leu (L)  46	  9.3%
Lys (K)  31	  6.2%
Met (M)  15	  3.0%
Phe (F)  26	  5.2%
Pro (P)  28	  5.6%
Ser (S)  23	  4.6%
Thr (T)  18	  3.6%
Trp (W)   2	  0.4%
Tyr (Y)  15	  3.0%
Val (V)  46	  9.3%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 61
Total number of positively charged residues (Arg + Lys): 55

Atomic composition:

Carbon      C	      2488
Hydrogen    H	      3930
Nitrogen    N	       658
Oxygen      O	       710
Sulfur      S	        22

Formula: C2488H3930N658O710S22
Total number of atoms: 7808

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    33725
Abs 0.1% (=1 g/l)   0.612, assuming all pairs of Cys residues form cystines


Ext. coefficient    33350
Abs 0.1% (=1 g/l)   0.605, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 32.59
This classifies the protein as stable.



Aliphatic index: 98.41

Grand average of hydropathicity (GRAVY): -0.008