ProtParam
User-provided sequence:
10 20 30 40 50 60
MSAVPSVQTF GKKKSATAVA HVKAGKGLIK VNGSPITLVE PEILRFKVYE PLLLVGLDKF
70 80 90 100 110 120
SNIDIRVRVT GGGHVSQVYA IRQAIAKGLV AYHQKYVDEQ SKNELKKAFT SYDRTLLIAD
130 140
SRRPEPKKFG GKGARSRFQK SYR
References and
documentation are available.
Number of amino acids: 143
Molecular weight: 15847.46
Theoretical pI: 10.26
Total number of negatively charged residues (Asp + Glu): 11
Total number of positively charged residues (Arg + Lys): 27
Atomic composition:
Carbon C 716
Hydrogen H 1167
Nitrogen N 205
Oxygen O 198
Sulfur S 1
Formula: C
716H
1167N
205O
198S
1
Total number of atoms: 2287
Extinction coefficients:
This protein does not contain any Trp residues. Experience shows that
this could result in more than 10% error in the computed extinction coefficient.
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 8940
Abs 0.1% (=1 g/l) 0.564
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 42.29
This classifies the protein as unstable.
Aliphatic index: 88.60
Grand average of hydropathicity (GRAVY): -0.344