ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSCCKVPVLI EAQVEMVSAN ELENKSLFRQ EEDATQTKEA SLMEQGSLST SFPQHTPKAP 

        70         80         90        100        110        120 
KNSVLNSIKI VIFCNKLNLL LPFGPLAILV HYMIDSKGWV FLLTLVGITP LAERLGYATE 

       130        140        150        160        170        180 
QLACYTGPTV GGLLNATFGN VTELIISIFA LKNGMIRVVQ LTLLGSILSN MLLVLGCAFF 

       190        200        210        220        230        240 
CGGLVFYQKD QVFDKGIATV NSGLLLMAVM GILFPAVLHY THSEVHAGSS ELALSRFSSC 

       250        260        270        280        290        300 
IMLIAYAAYL FFQLKSQSNS YSPLDEESNQ NEETSAEDED PEISKWEAII WLSILTAWVS 

       310        320        330        340        350        360 
LLSGYLVDAI EGASVSWNIP IAFISTILLP IVGNAAEHAG AIMFAMKDKL DLSLGVAIGS 

       370        380        390        400        410        420 
SIQISMFAVP FCVVIGWMMG QQMDLNFQLF ETAMLFITVI VVAFFLQEGS SNYFKGLMLI 

       430        440 
LCYLIVAASF FVHEDPHQDG I 

References and documentation are available.

Number of amino acids: 441

Molecular weight: 48215.38

Theoretical pI: 4.72

Amino acid composition: 
Ala (A)  37	  8.4%
Arg (R)   4	  0.9%
Asn (N)  18	  4.1%
Asp (D)  13	  2.9%
Cys (C)   9	  2.0%
Gln (Q)  18	  4.1%
Glu (E)  26	  5.9%
Gly (G)  29	  6.6%
His (H)   8	  1.8%
Ile (I)  36	  8.2%
Leu (L)  59	 13.4%
Lys (K)  16	  3.6%
Met (M)  17	  3.9%
Phe (F)  27	  6.1%
Pro (P)  15	  3.4%
Ser (S)  40	  9.1%
Thr (T)  19	  4.3%
Trp (W)   6	  1.4%
Tyr (Y)  11	  2.5%
Val (V)  33	  7.5%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 39
Total number of positively charged residues (Arg + Lys): 20

Atomic composition:

Carbon      C	      2207
Hydrogen    H	      3449
Nitrogen    N	       527
Oxygen      O	       626
Sulfur      S	        26

Formula: C2207H3449N527O626S26
Total number of atoms: 6835

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    49890
Abs 0.1% (=1 g/l)   1.035, assuming all pairs of Cys residues form cystines


Ext. coefficient    49390
Abs 0.1% (=1 g/l)   1.024, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 39.63
This classifies the protein as stable.



Aliphatic index: 114.10

Grand average of hydropathicity (GRAVY): 0.573