ProtParam
User-provided sequence:
10 20 30 40 50 60
MSDEAKEKRE LESQKESSHN KSEKSVEPKP KRRRRRNYDD YDAEVAKEET KAKNGLTKSE
70 80 90 100 110 120
NNGTVEDSES DMDDAKLDAL MGNEGEEEED DLAEIDTSNI ITSGRRTRGK VIDYKKTAEE
130 140 150
LDKKEPSTGS KDDVGYGEKE EDDEDEEDDD FKE
References and
documentation are available.
Number of amino acids: 153
Molecular weight: 17462.50
Theoretical pI: 4.44
Total number of negatively charged residues (Asp + Glu): 51
Total number of positively charged residues (Arg + Lys): 29
Atomic composition:
Carbon C 719
Hydrogen H 1156
Nitrogen N 210
Oxygen O 289
Sulfur S 3
Formula: C
719H
1156N
210O
289S
3
Total number of atoms: 2377
Extinction coefficients:
This protein does not contain any Trp residues. Experience shows that
this could result in more than 10% error in the computed extinction coefficient.
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 5960
Abs 0.1% (=1 g/l) 0.341
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 71.23
This classifies the protein as unstable.
Aliphatic index: 40.20
Grand average of hydropathicity (GRAVY): -1.785