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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSDLLPLATY SLNVEPYTPV PAIDVTMPIT VRITMAALNP EAIDEENKPS TLRIIKRNPD

70 80 90 100 110 120
FEDDDFLGGD FDEDEIDEES SEEEEEEKTQ KKKKSKGKKA ESESEDDEED DDEDDEFQES

130 140 150 160 170 180
VLLTLSPEAQ YQQSLDLTIT PEEEVQFIVT GSYAISLSGN YVKHPFDTPM GVEGEDEDED

190 200 210 220 230 240
ADIYDSEDYD LTPDEDEIIG DDMDDLDDEE EEEVRIEEVQ EEDEEDNDGE EEQEEEEEEE

250 260 270 280 290 300
QKEEVKPEPK KSKKEKKRKH EEKEEEKKAK KVKKVEFKKD LEEGPTKPKS KKEQDKHKPK

310 320 330 340 350 360
SKVLEGGIVI EDRTIGDGPQ AKRGARVGMR YIGKLKNGKV FDKNTSGKPF AFKLGRGEVI

370 380 390 400 410
KGWDIGVAGM SVGGERRIII PAPYAYGKQA LPGIPANSEL TFDVKLVSMK N


References and documentation are available.

Number of amino acids: 411 Molecular weight: 46553.09 Theoretical pI: 4.36
Amino acid composition: 
Ala (A) 18 4.4% Arg (R) 12 2.9% Asn (N) 10 2.4% Asp (D) 45 10.9% Cys (C) 0 0.0% Gln (Q) 12 2.9% Glu (E) 73 17.8% Gly (G) 28 6.8% His (H) 3 0.7% Ile (I) 24 5.8% Leu (L) 22 5.4% Lys (K) 48 11.7% Met (M) 8 1.9% Phe (F) 11 2.7% Pro (P) 24 5.8% Ser (S) 22 5.4% Thr (T) 17 4.1% Trp (W) 1 0.2% Tyr (Y) 10 2.4% Val (V) 23 5.6% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 118 Total number of positively charged residues (Arg + Lys): 60 Atomic composition: Carbon C 2018 Hydrogen H 3190 Nitrogen N 524 Oxygen O 719 Sulfur S 8 Formula: C2018H3190N524O719S8 Total number of atoms: 6459 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 20400 Abs 0.1% (=1 g/l) 0.438 Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 63.64 This classifies the protein as unstable. Aliphatic index: 64.26 Grand average of hydropathicity (GRAVY): -1.137