ProtParam
User-provided sequence:
10 20 30 40 50 60
MSDLLPLATY SLNVEPYTPV PAIDVTMPIT VRITMAALNP EAIDEENKPS TLRIIKRNPD
70 80 90 100 110 120
FEDDDFLGGD FDEDEIDEES SEEEEEEKTQ KKKKSKGKKA ESESEDDEED DDEDDEFQES
130 140 150 160 170 180
VLLTLSPEAQ YQQSLDLTIT PEEEVQFIVT GSYAISLSGN YVKHPFDTPM GVEGEDEDED
190 200 210 220 230 240
ADIYDSEDYD LTPDEDEIIG DDMDDLDDEE EEEVRIEEVQ EEDEEDNDGE EEQEEEEEEE
250 260 270 280 290 300
QKEEVKPEPK KSKKEKKRKH EEKEEEKKAK KVKKVEFKKD LEEGPTKPKS KKEQDKHKPK
310 320 330 340 350 360
SKVLEGGIVI EDRTIGDGPQ AKRGARVGMR YIGKLKNGKV FDKNTSGKPF AFKLGRGEVI
370 380 390 400 410
KGWDIGVAGM SVGGERRIII PAPYAYGKQA LPGIPANSEL TFDVKLVSMK N
References and
documentation are available.
Number of amino acids: 411
Molecular weight: 46553.09
Theoretical pI: 4.36
Total number of negatively charged residues (Asp + Glu): 118
Total number of positively charged residues (Arg + Lys): 60
Atomic composition:
Carbon C 2018
Hydrogen H 3190
Nitrogen N 524
Oxygen O 719
Sulfur S 8
Formula: C
2018H
3190N
524O
719S
8
Total number of atoms: 6459
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 20400
Abs 0.1% (=1 g/l) 0.438
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 63.64
This classifies the protein as unstable.
Aliphatic index: 64.26
Grand average of hydropathicity (GRAVY): -1.137