ProtParam
User-provided sequence:
10 20 30 40 50 60
MSDLVNKKFP AGDYKFQYIA ISQSDADSES CKMPQTVEWS KLISENKKVI ITGAPAAFSP
70 80 90 100 110 120
TCTVSHIPGY INYLDELVKE KEVDQVIVVT VDNPFANQAW AKSLGVKDTT HIKFASDPGC
130 140 150 160 170
AFTKSIGFEL AVGDGVYWSG RWAMVVENGI VTYAAKETNP GTDVTVSSVE SVLAHL
References and
documentation are available.
Number of amino acids: 176
Molecular weight: 19114.67
Theoretical pI: 5.01
Total number of negatively charged residues (Asp + Glu): 21
Total number of positively charged residues (Arg + Lys): 15
Atomic composition:
Carbon C 860
Hydrogen H 1331
Nitrogen N 215
Oxygen O 265
Sulfur S 6
Formula: C
860H
1331N
215O
265S
6
Total number of atoms: 2677
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 31065
Abs 0.1% (=1 g/l) 1.625, assuming all pairs of Cys residues form cystines
Ext. coefficient 30940
Abs 0.1% (=1 g/l) 1.619, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 34.33
This classifies the protein as stable.
Aliphatic index: 84.15
Grand average of hydropathicity (GRAVY): -0.048