ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSDLVTKFES LIISKYPVSF TKEQSAQAAQ WESVLKSGQI QPHLDQLNLV LRDNTFIVST 

        70         80         90        100        110        120 
LYPTSTDVHV FEVALPLIKD LVASSKDVKS TYTTYRHILR WIDYMQNLLE VSSTDKLEIN 

       130        140        150        160        170        180 
HDLDLPHEVI EKKKKAPAGG AADAAAKADE DVSKKAKKQD HPRGKPDEET LKKLREEAKA 

       190        200        210        220        230        240 
KKAAKKAANA KQQQEQQNKA PEKPKPSAID FRVGFIQKAI KHPDADSLYV STIDVGDEEG 

       250        260        270        280        290        300 
PRTVCSGLVK HFPLDAMQER YVVVVCNLKP VNMRGIKSTA MVLCGSNDDK VEFVEPPKDS 

       310        320        330        340        350        360 
KAGDKVFFEG FGDEAPMKQL NPKKKIWEHL QPHFTTNDGL EVIFKDEEEK DHPVRKLTNA 

       370 
KGESFKVASI ANAQVR 

References and documentation are available.

Number of amino acids: 376

Molecular weight: 42084.01

Theoretical pI: 7.69

Amino acid composition: 
Ala (A)  33	  8.8%
Arg (R)  11	  2.9%
Asn (N)  13	  3.5%
Asp (D)  29	  7.7%
Cys (C)   3	  0.8%
Gln (Q)  18	  4.8%
Glu (E)  28	  7.4%
Gly (G)  15	  4.0%
His (H)  11	  2.9%
Ile (I)  17	  4.5%
Leu (L)  28	  7.4%
Lys (K)  47	 12.5%
Met (M)   6	  1.6%
Phe (F)  14	  3.7%
Pro (P)  21	  5.6%
Ser (S)  24	  6.4%
Thr (T)  17	  4.5%
Trp (W)   3	  0.8%
Tyr (Y)   7	  1.9%
Val (V)  31	  8.2%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 57
Total number of positively charged residues (Arg + Lys): 58

Atomic composition:

Carbon      C	      1872
Hydrogen    H	      2996
Nitrogen    N	       512
Oxygen      O	       570
Sulfur      S	         9

Formula: C1872H2996N512O570S9
Total number of atoms: 5959

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    27055
Abs 0.1% (=1 g/l)   0.643, assuming all pairs of Cys residues form cystines


Ext. coefficient    26930
Abs 0.1% (=1 g/l)   0.640, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 32.32
This classifies the protein as stable.



Aliphatic index: 79.36

Grand average of hydropathicity (GRAVY): -0.606