ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSDMLPLATY SLNVEPYSPT PALNFKIPVT IRITMAAIDP EPFDDDKKPS TLRIIKRNPE 

        70         80         90        100        110        120 
LTRGEYYNQD NNDGLEEDES ESEQEADVPK RSVKSKKGKA VEQSESEDSE DENEIDDEFE 

       130        140        150        160        170        180 
ECVLLTLSPK GQYQQALDIT IAPEEDVQFV VTGSYTISLT GNYVKHPFDN SSDSDEDEED 

       190        200        210        220        230        240 
YYSDEESSNG EEEEEEEEED DEELSSGDDD LDDLVDASDI ESRLDELVKK DEKKKNNKKD 

       250        260        270        280        290        300 
SKRKHEEDEE ESAKPAEKKQ TTKKDKKAEK VKDSEESKPK PKTKLLEGGI IIEDRVTGKG 

       310        320        330        340        350        360 
PHAKKGTRVG MRYVGKLKNG KVFDKNTKGK PFVFKLGQGE VIKGWDIGVA GMAVGGERRI 

       370        380        390 
VIPAPYAYGK QALPGIPANS ELTFDVKLVS MK 

References and documentation are available.

Number of amino acids: 392

Molecular weight: 43903.41

Theoretical pI: 4.58

Amino acid composition: 
Ala (A)  19	  4.8%
Arg (R)  12	  3.1%
Asn (N)  15	  3.8%
Asp (D)  40	 10.2%
Cys (C)   1	  0.3%
Gln (Q)  10	  2.6%
Glu (E)  54	 13.8%
Gly (G)  26	  6.6%
His (H)   3	  0.8%
Ile (I)  19	  4.8%
Leu (L)  24	  6.1%
Lys (K)  47	 12.0%
Met (M)   6	  1.5%
Phe (F)   9	  2.3%
Pro (P)  22	  5.6%
Ser (S)  30	  7.7%
Thr (T)  18	  4.6%
Trp (W)   1	  0.3%
Tyr (Y)  12	  3.1%
Val (V)  24	  6.1%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 94
Total number of positively charged residues (Arg + Lys): 59

Atomic composition:

Carbon      C	      1904
Hydrogen    H	      3029
Nitrogen    N	       507
Oxygen      O	       666
Sulfur      S	         7

Formula: C1904H3029N507O666S7
Total number of atoms: 6113

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    23380
Abs 0.1% (=1 g/l)   0.533, assuming all pairs of Cys residues form cystines


Ext. coefficient    23380
Abs 0.1% (=1 g/l)   0.533, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 56.60
This classifies the protein as unstable.



Aliphatic index: 65.38

Grand average of hydropathicity (GRAVY): -1.049