ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSDQINVLSM QQQQQQQQQQ QQVYMSPQAE NLNHMYLLVN KLVKQLRENQ AEKAKILRNI 

        70         80         90        100        110        120 
DILSGSLNKY ETSEEPHDTT ENIALFNRFL EQRGKAPITE KEQLSNNLDE NAKDDVMLGV 

       130        140        150        160        170        180 
LKRQNSMLRK SLQESKQVTL ESMDLLSYSE DSLNYIVAQL RGNILMHHKE TIKLIRQKFQ 

       190        200        210        220 
TETIPLEDEE FKMYLENVNG LQKLTDISHT YRLLLRLHAQ D 

References and documentation are available.

Number of amino acids: 221

Molecular weight: 25915.43

Theoretical pI: 5.73

Amino acid composition: 
Ala (A)   8	  3.6%
Arg (R)  10	  4.5%
Asn (N)  17	  7.7%
Asp (D)  11	  5.0%
Cys (C)   0	  0.0%
Gln (Q)  26	 11.8%
Glu (E)  20	  9.0%
Gly (G)   5	  2.3%
His (H)   6	  2.7%
Ile (I)  12	  5.4%
Leu (L)  32	 14.5%
Lys (K)  16	  7.2%
Met (M)   9	  4.1%
Phe (F)   4	  1.8%
Pro (P)   4	  1.8%
Ser (S)  15	  6.8%
Thr (T)  10	  4.5%
Trp (W)   0	  0.0%
Tyr (Y)   7	  3.2%
Val (V)   9	  4.1%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 31
Total number of positively charged residues (Arg + Lys): 26

Atomic composition:

Carbon      C	      1126
Hydrogen    H	      1834
Nitrogen    N	       322
Oxygen      O	       359
Sulfur      S	         9

Formula: C1126H1834N322O359S9
Total number of atoms: 3650

Extinction coefficients:

This protein does not contain any Trp residues. Experience shows that
this could result in more than 10% error in the computed extinction coefficient.

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    10430
Abs 0.1% (=1 g/l)   0.402

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 66.43
This classifies the protein as unstable.



Aliphatic index: 93.08

Grand average of hydropathicity (GRAVY): -0.751