ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSDQPPAENA DVRQRRAPES PVTERLRAPA RDDARPTSDE SDMEGILQDE DRLERLTQAI 

        70         80         90        100        110        120 
PQDKGSLGVF ADSMLEALPP RWRNWVVRGL FSIIMISTFT FIVTRGATWL MFLVFLIQFK 

       130        140        150        160        170        180 
CFQEIISIGL AVYRLYDFPW FRALSWYFLL TSNYFFFGES LIDYWGIVLK KDNFLHFLVA 

       190        200        210        220        230        240 
YHRLVSFALY CIGFVSFVLS LRKGYYMRQF SLFAWTHLTL LLIVSQSFFI IQNIFQGLIW 

       250        260        270        280        290        300 
FLAPVAMIIC CDIMSYMFGF FWGKTPLIKL SPKKTWEGFI GGAFSTVVFG ILLSLALYNR 

       310        320        330        340        350        360 
PFFVCPVQHY QTDSSNCTIP LAFQLQDYPV PRPFSFVYKI LRKEPIIQLC PFVFHSIALS 

       370        380        390        400        410        420 
LFASILGPFG GFFASGFKRA FKIKDFGDVI PGHGGLMDRF DCQLLMGTFV MVYIHSFIRV 

       430        440        450 
PDASKLLKQI MTLEPQDQLN IFNLLQSELS KTGLI 

References and documentation are available.

Number of amino acids: 455

Molecular weight: 52441.62

Theoretical pI: 8.68

Amino acid composition: 
Ala (A)  25	  5.5%
Arg (R)  24	  5.3%
Asn (N)   9	  2.0%
Asp (D)  22	  4.8%
Cys (C)   8	  1.8%
Gln (Q)  21	  4.6%
Glu (E)  14	  3.1%
Gly (G)  27	  5.9%
His (H)   7	  1.5%
Ile (I)  37	  8.1%
Leu (L)  55	 12.1%
Lys (K)  17	  3.7%
Met (M)  13	  2.9%
Phe (F)  49	 10.8%
Pro (P)  25	  5.5%
Ser (S)  33	  7.3%
Thr (T)  18	  4.0%
Trp (W)  10	  2.2%
Tyr (Y)  15	  3.3%
Val (V)  26	  5.7%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 36
Total number of positively charged residues (Arg + Lys): 41

Atomic composition:

Carbon      C	      2469
Hydrogen    H	      3724
Nitrogen    N	       598
Oxygen      O	       624
Sulfur      S	        21

Formula: C2469H3724N598O624S21
Total number of atoms: 7436

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    77850
Abs 0.1% (=1 g/l)   1.485, assuming all pairs of Cys residues form cystines


Ext. coefficient    77350
Abs 0.1% (=1 g/l)   1.475, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 42.25
This classifies the protein as unstable.



Aliphatic index: 100.92

Grand average of hydropathicity (GRAVY): 0.364