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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSDQPPAENA DVRQRRAPES PVTERLRAPA RDDARPTSDE SDMEGILQDE DSDAGSKNKE

70 80 90 100 110 120
EKLERLTQAI PQDKGSLGVF ADSMLEALPP RWRNWVVRGL FSIIMISTFT FIVTRGATWL

130 140 150 160 170 180
MFLVFLIQFK CFQEIISIGL AVYRLYDFPW FRALSWYFLL TSNYFFFGES LIDYWGIVLK

190 200 210 220 230 240
KDNFLHFLVA YHRLVSFALY CIGFVSFVLS LRKGYYMRQF SLFAWTHLTL LLIVSQSFFI

250 260 270 280 290 300
IQNIFQGLIW FLAPVAMIIC CDIMSYMFGF FWGKTPLIKL SPKKTWEGFI GGAFSTVVFG

310 320 330 340 350 360
ILLSLALYNR PFFVCPVQHY QTDSSNCTIP LAFQLQDYPV PRPFSFVYKI LRKEPIIQLC

370 380 390 400 410 420
PFVFHSIALS LFASILGPFG GFFASGFKRA FKIKDFGDVI PGHGGLMDRF DCQLLMGTFV

430 440 450 460
MVYIHSFIRV PDASKLLKQI MTLEPQDQLN IFNLLQSELS KTGLI


References and documentation are available.

Number of amino acids: 465 Molecular weight: 53459.67 Theoretical pI: 8.51
Amino acid composition: 
Ala (A) 26 5.6% Arg (R) 23 4.9% Asn (N) 10 2.2% Asp (D) 23 4.9% Cys (C) 8 1.7% Gln (Q) 21 4.5% Glu (E) 16 3.4% Gly (G) 28 6.0% His (H) 7 1.5% Ile (I) 37 8.0% Leu (L) 55 11.8% Lys (K) 20 4.3% Met (M) 13 2.8% Phe (F) 49 10.5% Pro (P) 25 5.4% Ser (S) 35 7.5% Thr (T) 18 3.9% Trp (W) 10 2.2% Tyr (Y) 15 3.2% Val (V) 26 5.6% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 39 Total number of positively charged residues (Arg + Lys): 43 Atomic composition: Carbon C 2510 Hydrogen H 3791 Nitrogen N 609 Oxygen O 643 Sulfur S 21 Formula: C2510H3791N609O643S21 Total number of atoms: 7574 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 77850 Abs 0.1% (=1 g/l) 1.456, assuming all pairs of Cys residues form cystines Ext. coefficient 77350 Abs 0.1% (=1 g/l) 1.447, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 43.16 This classifies the protein as unstable. Aliphatic index: 98.97 Grand average of hydropathicity (GRAVY): 0.310