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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSDSPIELMR STLAGFQIAP DVKTISNIQD IRAQIQSFRE KELEGSQTKF KVLSRKLEIS

70 80 90 100 110 120
TQAMESLKQT AESSQHAEEI LSREKEKFRI AKLLNITENE IMSLESQLQK MKEQLLQLEE

130 140 150 160 170 180
RENTSEDICQ SEENANMLKL NFYHSLGFDL ETAENTGNKR VIIHTENDLQ TVQISNKYSP

190
YFYSNYFWDL LDDSKDKK


References and documentation are available.

Number of amino acids: 198 Molecular weight: 23038.90 Theoretical pI: 5.00
Amino acid composition: 
Ala (A) 9 4.5% Arg (R) 8 4.0% Asn (N) 12 6.1% Asp (D) 10 5.1% Cys (C) 1 0.5% Gln (Q) 15 7.6% Glu (E) 24 12.1% Gly (G) 4 2.0% His (H) 3 1.5% Ile (I) 15 7.6% Leu (L) 21 10.6% Lys (K) 17 8.6% Met (M) 6 3.0% Phe (F) 8 4.0% Pro (P) 3 1.5% Ser (S) 21 10.6% Thr (T) 11 5.6% Trp (W) 1 0.5% Tyr (Y) 5 2.5% Val (V) 4 2.0% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 34 Total number of positively charged residues (Arg + Lys): 25 Atomic composition: Carbon C 1005 Hydrogen H 1611 Nitrogen N 273 Oxygen O 331 Sulfur S 7 Formula: C1005H1611N273O331S7 Total number of atoms: 3227 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 12950 Abs 0.1% (=1 g/l) 0.562, assuming all pairs of Cys residues form cystines Ext. coefficient 12950 Abs 0.1% (=1 g/l) 0.562, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 68.15 This classifies the protein as unstable. Aliphatic index: 81.31 Grand average of hydropathicity (GRAVY): -0.743