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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSDTEEQEYE EEQAEDEEAV EEEAPEEPEP VAEREEERPK PSRPVVPPLI PPKIPEGERV

70 80 90 100 110 120
DFDDIHRKRM EKDLLELQTL IDVHFEQRKK EEEELIALKD RIERRRAERA EQQRFRTEKE

130 140 150 160 170 180
RERQAKLAEE KMRKEEEEAK KRAEDDAKKK KVLSNMGAHF GGYLVKAEQK RGKRQTGREM

190 200 210 220 230 240
KLRILSERKK PLNIDYMGED QLREKAQELS EWIHQLESEK FDLMEKLKQQ KYEINVLYNR

250 260
ISHAQKFRKG AGKGRVGGRW K


References and documentation are available.

Number of amino acids: 261 Molecular weight: 31215.23 Theoretical pI: 5.85
Amino acid composition: 
Ala (A) 17 6.5% Arg (R) 28 10.7% Asn (N) 4 1.5% Asp (D) 13 5.0% Cys (C) 0 0.0% Gln (Q) 15 5.7% Glu (E) 52 19.9% Gly (G) 12 4.6% His (H) 5 1.9% Ile (I) 11 4.2% Leu (L) 19 7.3% Lys (K) 32 12.3% Met (M) 7 2.7% Phe (F) 6 2.3% Pro (P) 12 4.6% Ser (S) 7 2.7% Thr (T) 4 1.5% Trp (W) 2 0.8% Tyr (Y) 5 1.9% Val (V) 10 3.8% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 65 Total number of positively charged residues (Arg + Lys): 60 Atomic composition: Carbon C 1351 Hydrogen H 2200 Nitrogen N 408 Oxygen O 427 Sulfur S 7 Formula: C1351H2200N408O427S7 Total number of atoms: 4393 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 18450 Abs 0.1% (=1 g/l) 0.591 Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 71.76 This classifies the protein as unstable. Aliphatic index: 62.45 Grand average of hydropathicity (GRAVY): -1.445