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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSDTEEQEYE EEQAEDEEAV EEEEAPEEPE PVAEREEERP KPSRPVVPPL IPPKIPEGER

70 80 90 100 110 120
VDFDDIHRKR MEKDLLELQT LIDVHFEQRK KEEEELIALK DRIERRRAER AEQQRFRTEK

130 140 150 160 170 180
ERERQAKLAE EKMRKEEEEA KKRAEDDAKK KKVLSNMGAH FGGYLVKAEQ KRGKRQTGRE

190 200 210 220 230 240
MKLRILSERK KPLNIDYMGE DQLREKAQEL SEWIHQLESE KFDLMEKLKQ QKYEINVLYN

250 260
RISHAQKFRK GAGKGRVGGR WK


References and documentation are available.

Number of amino acids: 262 Molecular weight: 31344.34 Theoretical pI: 5.74
Amino acid composition: 
Ala (A) 17 6.5% Arg (R) 28 10.7% Asn (N) 4 1.5% Asp (D) 13 5.0% Cys (C) 0 0.0% Gln (Q) 15 5.7% Glu (E) 53 20.2% Gly (G) 12 4.6% His (H) 5 1.9% Ile (I) 11 4.2% Leu (L) 19 7.3% Lys (K) 32 12.2% Met (M) 7 2.7% Phe (F) 6 2.3% Pro (P) 12 4.6% Ser (S) 7 2.7% Thr (T) 4 1.5% Trp (W) 2 0.8% Tyr (Y) 5 1.9% Val (V) 10 3.8% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 66 Total number of positively charged residues (Arg + Lys): 60 Atomic composition: Carbon C 1356 Hydrogen H 2207 Nitrogen N 409 Oxygen O 430 Sulfur S 7 Formula: C1356H2207N409O430S7 Total number of atoms: 4409 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 18450 Abs 0.1% (=1 g/l) 0.589 Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 72.77 This classifies the protein as unstable. Aliphatic index: 62.21 Grand average of hydropathicity (GRAVY): -1.453