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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSDTEKDKDV PMVDSHEATE EPPTTSTNTP SFPHLAQEQA KEESATLGAE VAHKKINYEQ

70 80 90 100 110 120
EAQKLEEKAL RFLAKQTHPV IIPSFASWFD ISKIHEIEKR SNPDFFNDSS RFKTPKAYKD

130 140 150 160 170 180
TRNFIINTYR LSPYEYLTIT AVRRNVAMDV ASIVKIHAFL EKWGLINYQI DPRTKPSLIG

190 200 210 220 230 240
PSFTGHFQVV LDTPQGLKPF LPENVIKQEV EGGDGAEPQV KKEFPVNLTI KKNVYDSAQD

250 260 270 280 290 300
FNALQDESRN SRQIHKVYIC HTCGNESINV RYHNLRARDT NLCSRCFQEG HFGANFQSSD

310 320 330 340 350 360
FIRLENNGNS VKKNWSDQEM LLLLEGIEMY EDQWEKIADH VGGHKRVEDC IEKFLSLPIE

370 380 390 400 410 420
DNYIREVVGS TLNGKGGDSR DGSVSGSKLM ECVNDAVQTL LQGDDKLGKV SDKSREISEK

430 440 450 460 470 480
YIEESQAIIQ ELVKLTMEKL ESKFTKLCDL ETQLEMEKLK YVKESEKMLN DRLSLSKQIL

490 500 510 520 530 540
DLNKSLEELN VSKKLVLISE QVDSGIQLVE KDQEGDDEDG NTATGHGVKR VGKEGEEVGE

550
GDSIAKLQPQ VYKPWSL


References and documentation are available.

Number of amino acids: 557 Molecular weight: 63168.05 Theoretical pI: 5.24
Amino acid composition: 
Ala (A) 25 4.5% Arg (R) 21 3.8% Asn (N) 29 5.2% Asp (D) 37 6.6% Cys (C) 7 1.3% Gln (Q) 28 5.0% Glu (E) 57 10.2% Gly (G) 32 5.7% His (H) 14 2.5% Ile (I) 33 5.9% Leu (L) 48 8.6% Lys (K) 51 9.2% Met (M) 9 1.6% Phe (F) 20 3.6% Pro (P) 21 3.8% Ser (S) 44 7.9% Thr (T) 26 4.7% Trp (W) 5 0.9% Tyr (Y) 14 2.5% Val (V) 36 6.5% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 94 Total number of positively charged residues (Arg + Lys): 72 Atomic composition: Carbon C 2778 Hydrogen H 4403 Nitrogen N 761 Oxygen O 887 Sulfur S 16 Formula: C2778H4403N761O887S16 Total number of atoms: 8845 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 48735 Abs 0.1% (=1 g/l) 0.772, assuming all pairs of Cys residues form cystines Ext. coefficient 48360 Abs 0.1% (=1 g/l) 0.766, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 41.82 This classifies the protein as unstable. Aliphatic index: 79.95 Grand average of hydropathicity (GRAVY): -0.667