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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSDVFDGYER QYCELSASLS KKCSSAISLD GEQKKQKLSE IKSGLENAEV LIRKMDLEAR

70 80 90 100 110 120
TLPPNLKSSL LVKLREFKSD LNNFKTEVKR ITSGQLNAAA RDELLEAGMA DTKTASADQR

130 140 150 160 170 180
ARLMMSTERL GRTTDRVKDS RRTMMETEEI GVSILQDLHG QRQSLLRAHE TLHGVDDNIG

190 200 210 220
KSKKILTDMT RRMNKNKWTI GAIIIALIAA IFIILYFKLT K


References and documentation are available.

Number of amino acids: 221 Molecular weight: 24950.87 Theoretical pI: 9.47
Amino acid composition: 
Ala (A) 17 7.7% Arg (R) 17 7.7% Asn (N) 8 3.6% Asp (D) 14 6.3% Cys (C) 2 0.9% Gln (Q) 8 3.6% Glu (E) 16 7.2% Gly (G) 11 5.0% His (H) 3 1.4% Ile (I) 16 7.2% Leu (L) 27 12.2% Lys (K) 21 9.5% Met (M) 9 4.1% Phe (F) 5 2.3% Pro (P) 2 0.9% Ser (S) 19 8.6% Thr (T) 15 6.8% Trp (W) 1 0.5% Tyr (Y) 3 1.4% Val (V) 7 3.2% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 30 Total number of positively charged residues (Arg + Lys): 38 Atomic composition: Carbon C 1081 Hydrogen H 1814 Nitrogen N 316 Oxygen O 335 Sulfur S 11 Formula: C1081H1814N316O335S11 Total number of atoms: 3557 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 10095 Abs 0.1% (=1 g/l) 0.405, assuming all pairs of Cys residues form cystines Ext. coefficient 9970 Abs 0.1% (=1 g/l) 0.400, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 39.17 This classifies the protein as stable. Aliphatic index: 92.76 Grand average of hydropathicity (GRAVY): -0.436