ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSEATLLSYT KKLLASPPQL SSTDLHDALL VILSLLQKCD TNSDESLSIY TKVSSFLTAL 

        70         80         90        100        110        120 
RVTKLDHKAE YIAEAAKAVL RHSDLVDLPL PKKDELHPED GPVILDIVGT GGDGQNTFNV 

       130        140        150        160        170        180 
STSAAIVASG IQGLKICKHG GKASTSNSGA GDLIGTLGCD MFKVNSSTVP KLWPDNTFMF 

       190        200        210        220        230        240 
LLAPFFHHGM GHVSKIRKFL GIPTVFNVLG PLLHPVSHVN KRILGVYSKE LAPEYAKAAA 

       250        260        270        280        290        300 
LVYPGSETFI VWGHVGLDEV SPIGKTTVWH IDPTSSELKL KTFQLEPSMF GLEEHELSKC 

       310        320        330        340        350        360 
ASYGPKENAR ILKEEVLSGK YHLGDNNPIY DYILMNTAVL YCLSQGHQNW KEGIIKAEES 

       370        380 
IHSGNALRSL EHFIDSVSSL 

References and documentation are available.

Number of amino acids: 380

Molecular weight: 41374.44

Theoretical pI: 6.18

Amino acid composition: 
Ala (A)  25	  6.6%
Arg (R)   6	  1.6%
Asn (N)  14	  3.7%
Asp (D)  19	  5.0%
Cys (C)   5	  1.3%
Gln (Q)   7	  1.8%
Glu (E)  22	  5.8%
Gly (G)  29	  7.6%
His (H)  17	  4.5%
Ile (I)  22	  5.8%
Leu (L)  49	 12.9%
Lys (K)  28	  7.4%
Met (M)   6	  1.6%
Phe (F)  13	  3.4%
Pro (P)  19	  5.0%
Ser (S)  38	 10.0%
Thr (T)  21	  5.5%
Trp (W)   4	  1.1%
Tyr (Y)  11	  2.9%
Val (V)  25	  6.6%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 41
Total number of positively charged residues (Arg + Lys): 34

Atomic composition:

Carbon      C	      1865
Hydrogen    H	      2941
Nitrogen    N	       485
Oxygen      O	       554
Sulfur      S	        11

Formula: C1865H2941N485O554S11
Total number of atoms: 5856

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    38640
Abs 0.1% (=1 g/l)   0.934, assuming all pairs of Cys residues form cystines


Ext. coefficient    38390
Abs 0.1% (=1 g/l)   0.928, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 34.09
This classifies the protein as stable.



Aliphatic index: 98.53

Grand average of hydropathicity (GRAVY): -0.045