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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSEATLSSKQ TIEWENKYSA HNYHPLPVVF HKAKGAHVWD PEGKLYLDFL SAYSAVNQGH

70 80 90 100 110 120
CHPHIIKALT EQAQTLTLSS RAFHNDVYAQ FAKFVTEFFG FETVLPMNTG AEAVETALKL

130 140 150 160 170 180
ARRWGYMKKN IPQDKAIILG AEGNFHGRTF GAISLSTDYE DSKLHFGPFV PNVASGHSVH

190 200 210 220 230 240
KIRYGHAEDF VPILESPEGK NVAAIILEPI QGEAGIVVPP ADYFPKVSAL CRKHNVLLIV

250 260 270 280 290 300
DEIQTGIGRT GELLCYDHYK AEAKPDIVLL GKALSGGVLP VSCVLSSHDI MSCFTPGSHG

310 320 330 340 350 360
STFGGNPLAS RVAIAALEVI RDEKLCQRAA QLGSSFIAQL KALQAKSNGI ISEVRGMGLL

370 380 390 400 410 420
TAIVIDPSKA NGKTAWDLCL LMKDHGLLAK PTHDHIIRLA PPLVISEEDL QTGVETIAKC


IDLL


References and documentation are available.

Number of amino acids: 424 Molecular weight: 46086.01 Theoretical pI: 6.46
Amino acid composition: 
Ala (A) 43 10.1% Arg (R) 12 2.8% Asn (N) 13 3.1% Asp (D) 19 4.5% Cys (C) 8 1.9% Gln (Q) 13 3.1% Glu (E) 25 5.9% Gly (G) 33 7.8% His (H) 20 4.7% Ile (I) 30 7.1% Leu (L) 44 10.4% Lys (K) 27 6.4% Met (M) 6 1.4% Phe (F) 17 4.0% Pro (P) 22 5.2% Ser (S) 29 6.8% Thr (T) 20 4.7% Trp (W) 4 0.9% Tyr (Y) 11 2.6% Val (V) 28 6.6% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 44 Total number of positively charged residues (Arg + Lys): 39 Atomic composition: Carbon C 2078 Hydrogen H 3267 Nitrogen N 557 Oxygen O 599 Sulfur S 14 Formula: C2078H3267N557O599S14 Total number of atoms: 6515 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 38890 Abs 0.1% (=1 g/l) 0.844, assuming all pairs of Cys residues form cystines Ext. coefficient 38390 Abs 0.1% (=1 g/l) 0.833, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 38.15 This classifies the protein as stable. Aliphatic index: 97.36 Grand average of hydropathicity (GRAVY): 0.010