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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSEEHIAVTR FREYLRVNTE QPNPDYAACR DFLFKYADEL GIARRSFETV PGAIFVIMTI

70 80 90 100 110 120
PGSQPELPSI MLYSHTDVVP TFREHWTHDP YSAFKDEDGN IFARGAQDMK CVGVQQMEAL

130 140 150 160 170 180
RNLFAQGIRQ WKRTIHLVWG PDEEIFGING MKGFAKTDEF KKLNLGFSLD EGMPSDDDVY

190 200 210 220 230 240
KVFYAERVAW WVKVTFPGNP GHGSQFMENT AMEKLERYLA SARKFRDEQK ALLESNPDLT

250 260 270 280 290 300
IGDVTTLNVN IVNGGVQFNV IPEKFEAFVD IRLTPSIDFN EMRNKLDQWV KDAGEGVTYE

310 320 330 340 350 360
FSKHSDLKLV TPHTRDDPFW VAFEDSLKQE KCKFTTEVLI GSTDSRIVRE AGVRAINFSP

370 380 390
LINTPLLAHA HNEFLNEKVF LRGIEIYQTL INNVANVNE


References and documentation are available.

Number of amino acids: 399 Molecular weight: 45679.73 Theoretical pI: 5.22
Amino acid composition: 
Ala (A) 26 6.5% Arg (R) 22 5.5% Asn (N) 23 5.8% Asp (D) 26 6.5% Cys (C) 3 0.8% Gln (Q) 13 3.3% Glu (E) 33 8.3% Gly (G) 24 6.0% His (H) 10 2.5% Ile (I) 23 5.8% Leu (L) 29 7.3% Lys (K) 22 5.5% Met (M) 10 2.5% Phe (F) 28 7.0% Pro (P) 19 4.8% Ser (S) 18 4.5% Thr (T) 23 5.8% Trp (W) 7 1.8% Tyr (Y) 10 2.5% Val (V) 30 7.5% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 59 Total number of positively charged residues (Arg + Lys): 44 Atomic composition: Carbon C 2057 Hydrogen H 3148 Nitrogen N 550 Oxygen O 605 Sulfur S 13 Formula: C2057H3148N550O605S13 Total number of atoms: 6373 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 53525 Abs 0.1% (=1 g/l) 1.172, assuming all pairs of Cys residues form cystines Ext. coefficient 53400 Abs 0.1% (=1 g/l) 1.169, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 31.06 This classifies the protein as stable. Aliphatic index: 79.15 Grand average of hydropathicity (GRAVY): -0.370